A Biomarker Database to Investigate Blood-Based and Digital Biomarkers in Participants Screened for Alzheimer's Disease (Bio-Hermes)
Public ClinicalTrials.gov record NCT04733989. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Development of a Biomarker Database to Investigate Aß, P-tau, and NfL Blood-Based Biomarkers and Digital Biomarkers in Older Participants Screened for Preclinical Alzheimer's Disease (AD), Prodromal AD, or Mild AD
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study (Bio-Hermes) is to develop a blood, digital, and brain amyloid PET scan biomarker database that can be used to determine whether a meaningful relationship exists between digital tests, blood amyloid-beta, p-tau, and neurofilament biomarker levels and amyloid-beta levels identified through brain amyloid PET images. Blood collected will also be genetically sequenced to gain insights about genes and brain amyloid. The Bio-Hermes study will include 1,000 volunteers over the age of 60 screened for Preclinical Alzheimer's Disease, Prodromal AD, or Mild Dementia AD, and includes an endpoint enrollment requirement of 200 participants from underrepresented minority populations.
Study identification
- NCT ID
- NCT04733989
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 1,002 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 60 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 20, 2021
- Primary completion
- Nov 10, 2022
- Completion
- Nov 10, 2022
- Last update posted
- Feb 8, 2023
2021 – 2022
United States locations
- U.S. sites
- 16
- U.S. states
- 5
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Visionary Investigators Network - Aventura | Aventura | Florida | 33180 | — |
| Visionary Investigators Network - Coral Gables | Coral Gables | Florida | 33133 | — |
| Charter Research - Lady Lake | Lady Lake | Florida | 32159 | — |
| JEM | Lake Worth | Florida | 33462 | — |
| ClinCloud | Maitland | Florida | 32751 | — |
| Visionary Investigators Network - South Miami | Miami | Florida | 33176 | — |
| K2 | Orlando | Florida | 32751 | — |
| Visionary Investigators Network - Pembroke Pines | Pembroke Pines | Florida | 33026 | — |
| Progressive Medical Research | Port Orange | Florida | 32127 | — |
| Axiom Clinical Research of Florida | Tampa | Florida | 33609 | — |
| Charter Research - Winter Park | Winter Park | Florida | 32792 | — |
| Great Lakes Clinical Trials | Chicago | Illinois | 60640 | — |
| Kansas University Alzheimer's Disease Center (KUADC) | Fairway | Kansas | 66160 | — |
| Velocity Clinical Research - Syracuse | Syracuse | New York | 13057 | — |
| Kerwin Research Center | Dallas | Texas | 75231 | — |
| El Faro Health and Therapeutics | Rio Grande City | Texas | 78582 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04733989, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 8, 2023 · Synced Sep 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04733989 live on ClinicalTrials.gov.