ClinicalTrials.gov record
Completed Phase 1 Interventional Results available

Testing the Combination of Two Immunotherapy Drugs (Magrolimab and Dinutuximab) in Patients With Relapsed or Refractory Neuroblastoma or Relapsed Osteosarcoma

ClinicalTrials.gov ID: NCT04751383

Public ClinicalTrials.gov record NCT04751383. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 20, 2026, 10:41 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 1 Trial of Hu5F9-G4 (Magrolimab) Combined With Dinutuximab in Children and Young Adults With Relapsed and Refractory Neuroblastoma or Relapsed Osteosarcoma

Study identification

NCT ID
NCT04751383
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
National Cancer Institute (NCI)
NIH
Enrollment
12 participants

Conditions and interventions

Interventions

  • Biospecimen Collection Procedure
  • Bone Marrow Aspiration Procedure
  • Bone Marrow Biopsy Procedure
  • Computed Tomography Procedure
  • Dinutuximab Biological
  • Magnetic Resonance Imaging Procedure
  • Magrolimab Biological
  • Resection Procedure

Procedure · Biological

Eligibility (public fields only)

Age range
2 Years to 35 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 30, 2021
Primary completion
Sep 29, 2024
Completion
Sep 29, 2024
Last update posted
Jan 20, 2026

2021 – 2024

United States locations

U.S. sites
9
U.S. states
7
U.S. cities
9
Facility City State ZIP Site status
Children's Hospital Los Angeles Los Angeles California 90027
Lucile Packard Children's Hospital Stanford University Palo Alto California 94304
UCSF Medical Center-Mission Bay San Francisco California 94158
Children's Hospital Colorado Aurora Colorado 80045
University of Chicago Comprehensive Cancer Center Chicago Illinois 60637
Dana-Farber Cancer Institute Boston Massachusetts 02215
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center Houston Texas 77030
Seattle Children's Hospital Seattle Washington 98105

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04751383, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 20, 2026 · Synced May 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04751383 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →