ClinicalTrials.gov record
LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve
ClinicalTrials.gov ID: NCT04752722
Public ClinicalTrials.gov record NCT04752722. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 7, 2026, 12:11 PM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2 Study of EG-70 as an Intravesical Administration to Patients With BCG Unresponsive Non-Muscle Invasive Bladder Cancer (NMIBC) and High-Risk NMIBC Patients Who Are BCG Naïve or Received Incomplete BCG Treatment
Study identification
- NCT ID
- NCT04752722
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- enGene, Inc.
- Industry
- Enrollment
- 350 participants
Conditions and interventions
Interventions
- EG-70 (phase 1) Drug
- EG-70 (phase 2) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 21, 2021
- Primary completion
- Jun 29, 2026
- Completion
- Nov 29, 2028
- Last update posted
- Apr 29, 2026
2021 – 2028
United States locations
- U.S. sites
- 49
- U.S. states
- 27
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The University of Alabama at Birmingham Clinical Research Unit (CRU) | Birmingham | Alabama | 35249 | Recruiting |
| Mayo Clinic | Scottsdale | Arizona | 85259 | Recruiting |
| Urological Associates of South Arizona | Tucson | Arizona | 85715 | Completed |
| Arkansas Urology | Little Rock | Arkansas | 72211 | Recruiting |
| University of California - Irvine Medical Center | Irvine | California | 92697 | Recruiting |
| UC San Diego Moores Cancer Center | La Jolla | California | 92037 | Recruiting |
| USC/Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | Recruiting |
| Tower Urology | Los Angeles | California | 90048 | Recruiting |
| Om Research | San Diego | California | 92123 | Recruiting |
| Colorado Clinical Research | Lakewood | Colorado | 80228 | Recruiting |
| The George Washington Medical Faculty Associates | Washington D.C. | District of Columbia | 20037 | Recruiting |
| University of Florida | Jacksonville | Florida | 32209 | Recruiting |
| Sylvester Comprehensive Cancer Center / University of Miami Hospital and Clinics | Miami | Florida | 33136 | Recruiting |
| Emory University | Atlanta | Georgia | 30322 | Recruiting |
| Rush University Medical Center | Chicago | Illinois | 60607 | Recruiting |
| Urology of Indiana | Greenwood | Indiana | 46143 | Recruiting |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | Recruiting |
| John Hopkins Hospital | Baltimore | Maryland | 21287 | Recruiting |
| Chesapeake Urology Research Associates | Hanover | Maryland | 21076 | Recruiting |
| Brigham and Women's Hospital | Boston | Massachusetts | 45227 | Recruiting |
| Henry Ford Health System | Detroit | Michigan | 48202 | Recruiting |
| Corewell Health Medical Group and Spectrum Health Hospitals | Grand Rapids | Michigan | 49503 | Recruiting |
| University of Minnesota | Minneapolis | Minnesota | 55455 | Recruiting |
| Mayo Clinic | Rochester | Minnesota | 55905 | Recruiting |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08901 | Recruiting |
| New Jersey Urology, LLC | Voorhees Township | New Jersey | 08043 | Recruiting |
| Albany Medical College | Albany | New York | 12208 | Recruiting |
| Mount Sinai Medical Center | New Haven | New York | 10029 | Recruiting |
| Laura & Isaac Perlmutter Cancer Center at NYU Langone Health | New York | New York | 10016 | Completed |
| Associated Medical Professionals of NY, | Syracuse | New York | 13210 | Recruiting |
| UNC Chapel Hill Hospital | Chapel Hill | North Carolina | 27514 | Recruiting |
| Duke Health - Duke Cancer Center | Durham | North Carolina | 27710 | Recruiting |
| Associated Urologists of North Carolina | Raleigh | North Carolina | 27612 | Recruiting |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45219 | Recruiting |
| Central Ohio Urology Group | Gahanna | Ohio | 43230 | Recruiting |
| Clinical Research Solutions - Helios Clinical Research | Middleburg Heights | Ohio | 44130 | Recruiting |
| Oregon Health & Science University (OHSU) | Portland | Oregon | 97239 | Recruiting |
| Thomas Jefferson University, Sidney Kimmel Cancer Center | Philadelphia | Pennsylvania | 19107 | Recruiting |
| Carolina Urologic Research Center, LLC | Myrtle Beach | South Carolina | 29572 | Recruiting |
| Urology Associates, P.C. | Nashville | Tennessee | 37209 | Recruiting |
| Vanderbilt Univerity Medical Center | Nashville | Tennessee | 37232 | Recruiting |
| Urology Austin | Austin | Texas | 78745 | Recruiting |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | Recruiting |
| Houston Metro Urology | Houston | Texas | 77027 | Recruiting |
| Houston Methodist Hospital - Department of Urology | Houston | Texas | 77030 | Recruiting |
| University of Texas - MD Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| Huntsman Cancer Institute, University of Utah | Salt Lake City | Utah | 84112 | Recruiting |
| University of Virginia Comprehensive Cancer Center | Charlottesville | Virginia | 22903 | Recruiting |
| Froedtert Hospital / Medical College of Wisconsin | Milwaukee | Wisconsin | 52336 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 52 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04752722, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 29, 2026 · Synced May 7, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04752722 live on ClinicalTrials.gov.