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Active, not recruiting Phase 1 Interventional

Study to Assess the Safety and Tolerability of CFT7455 in Relapsed/Refractory Non-Hodgkin's Lymphoma or Multiple Myeloma

ClinicalTrials.gov ID: NCT04756726

Public ClinicalTrials.gov record NCT04756726. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 22, 2026, 11:44 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1/2 Open-Label Multi-Center Study to Characterize the Safety and Tolerability of CFT7455 in Subjects With Relapsed/Refractory Non-Hodgkin's Lymphoma or Multiple Myeloma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to characterize the safety, tolerability, pharmacokinetics, pharmacodynamics, and antitumor activity of oral cemsidomide (also known as CFT7455) administered at different dosages in subjects with Relapsed/Refractory (r/r) Non-Hodgkin's Lymphoma (NHL) or Multiple Myeloma (MM). Cemsidomide may be administered as a single agent and, in MM only, in combination with oral dexamethasone.

Study identification

NCT ID
NCT04756726
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 1
Lead sponsor
C4 Therapeutics, Inc.
Industry
Enrollment
224 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 27, 2021 (Actual)
Primary completion
Sep 30, 2026 (Estimated)
Completion
Dec 31, 2026 (Estimated)
Last update posted
Mar 25, 2026

2021 – 2026

United States locations

U.S. sites
13
U.S. states
11
U.S. cities
11
Facility City State ZIP Site status
Mayo Clinic Phoenix Arizona 85054 —
University of California-San Francisco San Francisco California 94143 —
Colorado Blood Cancer Institute (Sarah Cannon Research Institute) Denver Colorado 80218 —
Mayo Clinic Jacksonville Florida 32224 —
Emory University Hospital Atlanta Georgia 30322 —
Massachusetts General Hospital Boston Massachusetts 02114 —
Dana-Farber Cancer Institute Boston Massachusetts 02215 —
Mayo Clinic Rochester Minnesota 55905 —
Washington University School of St. Louis St Louis Missouri 63110 —
Mt Sinai Medical Center New York New York 10029 —
Memorial Sloan Kettering Cancer Center New York New York 10065 —
Tennessee Oncology (Sarah Cannon Research Institute) Nashville Tennessee 37203 —
Medical College of Wisconsin Milwaukee Wisconsin 53226 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04756726, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 25, 2026 · Synced Oct 22, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04756726 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →