ClinicalTrials.gov record
An Extension Study to Evaluate the Long-term Safety and Efficacy of Pegcetacoplan (APL-2) in Subjects With Geographic Atrophy Secondary to AMD
ClinicalTrials.gov ID: NCT04770545
Public ClinicalTrials.gov record NCT04770545. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced Apr 22, 2026, 6:19 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Pegcetacoplan in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration
Study identification
- NCT ID
- NCT04770545
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Apellis Pharmaceuticals, Inc.
- Industry
- Enrollment
- 792 participants
Conditions and interventions
Interventions
- PEGCETACOPLAN (APL-2) Drug
Drug
Eligibility (public fields only)
- Age range
- 60 Years and older
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 3, 2021
- Primary completion
- Sep 4, 2025
- Completion
- Sep 4, 2025
- Last update posted
- Oct 23, 2025
2021 – 2025
United States locations
- U.S. sites
- 99
- U.S. states
- 29
- U.S. cities
- 85
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retinal Research Institue, LLC | Phoenix | Arizona | 85014 | — |
| Associated Retina Consultants, Ltd. | Phoenix | Arizona | 85020 | — |
| California Retina Consultants | Bakersfield | California | 93309 | — |
| Retinal Diagnostic Center | Campbell | California | 95508 | — |
| The Retina Partners | Encino | California | 91436 | — |
| Retina Consultants of Orange County | Fullerton | California | 92835 | — |
| Atlantis Eyecare | Huntington Beach | California | 92647 | — |
| Jacobs Retina Center, UCSD | La Jolla | California | 92093 | — |
| Doheny Eye Center UCLA | Los Angeles | California | 90033 | — |
| Northern California Retina Vitreous Associates | Mountain View | California | 94040 | — |
| Retina Institute of California Medical Group | Palm Desert | California | 92260 | — |
| Byers Eye Institute, Stanford University | Palo Alto | California | 94303 | — |
| Retina Consultants San Diego | Poway | California | 92064 | — |
| Orange County Retina Medical Group | Santa Ana | California | 92705 | — |
| California Retina Consultants | Santa Barbara | California | 93103 | — |
| Bay Area Retina Associates | Walnut Creek | California | 94598 | — |
| Southwest Retina Research Center, LLC | Durango | Colorado | 81301 | — |
| Danbury Eye Physicians & Surgeons, PC | Danbury | Connecticut | 06810 | — |
| Retina Group of New England - New London | Waterford | Connecticut | 06835 | — |
| Florida Eye Microsurgical Institute, Inc. | Boynton Beach | Florida | 33426 | — |
| Blue Ocean Clinical Research | Clearwater | Florida | 33761 | — |
| Pinnacle Research Insitute | Fort Lauderdale | Florida | 33309 | — |
| Retina Health Center | Fort Myers | Florida | 33907 | — |
| National Opthalmic Research Institute | Fort Myers | Florida | 33912 | — |
| Bascom Palmer Eye Institute | Miami | Florida | 33136 | — |
| Bascom Palmer Eye Institute at Naples | Naples | Florida | 34103 | — |
| Palm Beach Gardens | Palm Beach Gardens | Florida | 33418 | — |
| Retina Specialty Institute | Pensacola | Florida | 32503 | — |
| Eye Associates of Pinellas | Pinellas Park | Florida | 33782 | — |
| East Florida Eye Institute | Stuart | Florida | 34994 | — |
| Retina Associates of Florida | Tampa | Florida | 33609 | — |
| University of South Florida | Tampa | Florida | 33612 | — |
| Center for Retina and Macular Disease | Winter Haven | Florida | 33880 | — |
| Southeast Retina Center, PC | Augusta | Georgia | 30909 | — |
| Georgia Retina, PC | Marietta | Georgia | 30060 | — |
| Gailey Eye Clinic Retina Center | Bloomington | Illinois | 61704 | — |
| Northwestern Feinberg School of Medicine | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Midwest Eye Institute | Indianapolis | Indiana | 46290 | — |
| Retina and Vitreous Associates of Kentucky, PSC dba Retina Associates of Kentucky | Lexington | Kentucky | 40509 | — |
| The Retina Care Center | Baltimore | Maryland | 21209 | — |
| Elman Retina Group | Baltimore | Maryland | 21236 | — |
| The Retina Group of Washington | Chevy Chase | Maryland | 92705 | — |
| Cumberland Valley Retina Center | Hagerstown | Maryland | 21740 | — |
| Mid Atlantic Retina Specialist | Hagerstown | Maryland | 21740 | — |
| Ophthalmic Consultants of Boston | Boston | Massachusetts | 02114 | — |
| Tufts Medical Center | Boston | Massachusetts | 02116 | — |
| New England Retina Consultants, PC | Springfield | Massachusetts | 01107 | — |
| Michigan Medicine Kellogg Eye Center | Ann Arbor | Michigan | 48105 | — |
| Associated Retinal Consultants, PC | Grand Rapids | Michigan | 49546 | — |
| Associated Retinal Consultants, PC | Traverse City | Michigan | 49686 | — |
| Vitreoretinal Surgery | Minneapolis | Minnesota | 55435 | — |
| Sierra Eye Associates | Reno | Nevada | 89503 | — |
| Retina Center of NJ, LLC | Bloomfield | New Jersey | 07003 | — |
| NJ Retina | Teaneck | New Jersey | 07666 | — |
| NJ Retina | Toms River | New Jersey | 08755 | — |
| Vision Research Center Eye Associates of NM | Albuquerque | New Mexico | 87109 | — |
| Long Island Vitreoretinal Consultants | Great Neck | New York | 11021 | — |
| Vitreous Retina Macula Consultants of New York | New York | New York | 10022 | — |
| Ophthalmic Consultants of Long Island | Oceanside | New York | 11572 | — |
| Western Carolina Retinal Associates | Asheville | North Carolina | 28803 | — |
| Charlotte Eye Ear Nose and Throat Associates, PS | Charlotte | North Carolina | 28210 | — |
| Duke University, Duke Eye Center | Durham | North Carolina | 27710 | — |
| Graystone Eye | Hickory | North Carolina | 28602 | — |
| Retina Associates of Cleveland, Inc. | Cleveland | Ohio | 44122 | — |
| Retina Associates of Cleveland | Cleveland | Ohio | 44130 | — |
| Cleveland Clinic Cole Eye Institute | Cleveland | Ohio | 44195 | — |
| The Ohio State University | Columbus | Ohio | 43212 | — |
| Retina Associates of Cleveland, Inc. | Youngstown | Ohio | 44505 | — |
| Retina Vitreous Center, PLLC | Edmond | Oklahoma | 73013 | — |
| Oregon Retina LLP | Eugene | Oregon | 97405 | — |
| Retina Northwest, PC | Portland | Oregon | 97221 | — |
| Eye Health Northwest | Portland | Oregon | 97225 | — |
| Mid Atlantic Retina | Bethlehem | Pennsylvania | 18107 | — |
| Retina Vitreous Consultants | Monroeville | Pennsylvania | 15146 | — |
| Mid Atlantic Retina | Philadelphia | Pennsylvania | 19006 | — |
| Mid Atlantic Retina | Philadelphia | Pennsylvania | 19107 | — |
| AIO Visionary Eye Care | West Mifflin | Pennsylvania | 15122 | — |
| Black Hills Regional Eye Institute | Rapid City | South Dakota | 57701 | — |
| Charles Retina Institute | Germantown | Tennessee | 38138 | — |
| Tennessee Retina, PC | Nashville | Tennessee | 78503 | — |
| Retina Research Center PLLC | Austin | Texas | 78750 | — |
| Brown Retina Institute | Bellaire | Texas | 77401 | — |
| Texas Retina Associates | Dallas | Texas | 75231 | — |
| Houston Eye Associates | Houston | Texas | 77025 | — |
| Retina Consultants of Houston, PA | Houston | Texas | 77030 | — |
| Valley Retina Institute | McAllen | Texas | 78503 | — |
| Medical Center Ophthalmology Associates | San Antonio | Texas | 78240 | — |
| Retina Associates of South Texas | San Antonio | Texas | 78240 | — |
| Retina Consultants of Houston | The Woodlands | Texas | 77384 | — |
| Retina Associates of Utah, PC | Murray | Utah | 84107 | — |
| University of Utah - John A. Moran Center | Salt Lake City | Utah | 84312 | — |
| University of Virginia | Charlottesville | Virginia | 22903 | — |
| The Retina Group of Washington | Fairfax | Virginia | 22031 | — |
| Emerson Clinical Research Institute | Falls Church | Virginia | 22046 | — |
| Vitreoretinal Associates of Washington | Bellevue | Washington | 98004 | — |
| Spokane Eye Clinical Research | Spokane | Washington | 99204 | — |
| Retina Health Center | Madison | Wisconsin | 53705 | — |
| Retina-Vitreous Associates Medical Group | Madison | Wisconsin | 53705 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 76 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04770545, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 23, 2025 · Synced Apr 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04770545 live on ClinicalTrials.gov.