Pegloticase and Methotrexate Co-administered in Participants With Uncontrolled Gout Who Previously Failed Pegloticase Monotherapy
Public ClinicalTrials.gov record NCT04772313. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 4, Multicenter, Open-label, Efficacy and Safety Trial of Pegloticase and Methotrexate Co-administered in Patients With Uncontrolled Gout Who Have Previously Received Pegloticase Monotherapy But Did Not Maintain a Serum Uric Acid Response
Study identification
- NCT ID
- NCT04772313
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Lead sponsor
- Amgen
- Industry
- Enrollment
- 11 participants
Conditions and interventions
Conditions
Interventions
- Methotrexate (MTX) Drug
- Pegloticase Biological
Drug · Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 7, 2021
- Primary completion
- Aug 22, 2022
- Completion
- Apr 23, 2023
- Last update posted
- Jun 26, 2024
2021 – 2023
United States locations
- U.S. sites
- 15
- U.S. states
- 9
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham (UAB) - Center for Education & Research on Therapeutics of Musculoskeletal Disorders | Birmingham | Alabama | 35294-0002 | — |
| Arizona Arthritis and Rheumatology Associates | Flagstaff | Arizona | 86001 | — |
| Arizona Arthritis and Rheumatology Associates | Glendale | Arizona | 85306 | — |
| Arizona Arthritis and Rheumatology Associates | Mesa | Arizona | 85210 | — |
| East Bay Rheumatology Medical Group | San Leandro | California | 94578 | — |
| Providence St. John's Health Clinic | Santa Monica | California | 90404 | — |
| University of Colorado Anschutz Medical Campus | Aurora | Colorado | 80045-2536 | — |
| Life Clinical Trials | Margate | Florida | 33063 | — |
| IRIS Research and Development, LLC | Plantation | Florida | 33324 | — |
| Napa Research | Pompano Beach | Florida | 33046 | — |
| GCP Clinical Research, LLC | Tampa | Florida | 33609 | — |
| The Center for Rheumatology and Bone Research | Wheaton | Maryland | 20902 | — |
| Altoona Center for Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| Biopharma Informatic, LLC | Houston | Texas | 77043 | — |
| Western Washington Arthritis Clinic | Bothell | Washington | 98021 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04772313, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 26, 2024 · Synced May 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04772313 live on ClinicalTrials.gov.