A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease
Public ClinicalTrials.gov record NCT04777331. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Phase IIB, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multicenter, randomized, double-blind, placebo-controlled study that will evaluate the efficacy and safety of intravenous (IV) prasinezumab versus placebo in participants with Early Parkinson's Disease (PD) who are on stable symptomatic PD medication.
Study identification
- NCT ID
- NCT04777331
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 586 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 5, 2021 (Actual)
- Primary completion
- Sep 11, 2024 (Actual)
- Completion
- Jun 30, 2031 (Estimated)
- Last update posted
- Sep 4, 2026
2021 – 2031
United States locations
- U.S. sites
- 31
- U.S. states
- 18
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| Neurology Center of North Orange County | Fullerton | California | 92835 | — |
| UC San Diego | La Jolla | California | 92037 | — |
| Keck School of Medicine of USC | Los Angeles | California | 90033 | — |
| Cedars Sinai Medical Center | Los Angeles | California | 90048 | — |
| University of California San Francisco | San Francisco | California | 94143 | — |
| CenExel Rocky Mountain Clinical Research, LLC | Englewood | Colorado | 80113 | — |
| Institute for Neurodegenerative Disorders | New Haven | Connecticut | 06510 | — |
| JEM Research LLC | Atlantis | Florida | 33462 | — |
| Parkinson's Disease and Movement Disorders Center of Boca Raton | Boca Raton | Florida | 33486 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| University of South Florida | Tampa | Florida | 33613-4706 | — |
| Charter Research - Winter Park/Orlando | Winter Park | Florida | 32792 | — |
| Northwestern University Feinberg School Of Medicine | Chicago | Illinois | 60611 | — |
| Southern Illinois University, School of Medicine | Springfield | Illinois | 62702 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114-2759 | — |
| Quest Research Institute | Farmington Hills | Michigan | 48334 | — |
| Henry Ford Hospital | West Bloomfield | Michigan | 48322 | — |
| Dent Neurological Institute | Amherst | New York | 14226 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| The Movement Disorder Clinic of Oklahoma | Tulsa | Oklahoma | 74136 | — |
| University Pennsylvania Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Texas Neurology PA | Dallas | Texas | 75206 | — |
| Baylor College of Medicine Medical Center | Houston | Texas | 77030 | — |
| Central Texas Neurology Consultants | Round Rock | Texas | 78681 | — |
| University of Vermont Medical Center | Burlington | Vermont | 05401 | — |
| Sentara Neurology Specialists | Norfolk | Virginia | 23507 | — |
| EvergreenHealth Investigational Drug Services | Kirkland | Washington | 98034 | — |
| Inland Northwest Research | Spokane | Washington | 99202 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 79 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04777331, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 4, 2026 · Synced Nov 9, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04777331 live on ClinicalTrials.gov.