Solriamfetol's Effect on Cognitive Health in Apnea Participants During a Randomized Placebo-controlled Study
Public ClinicalTrials.gov record NCT04789174. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Solriamfetol's Effect on Cognitive Health in Apnea Participants During a Randomized Placebo-controlled Study (SHARP): a 5-Week Double-blind, Placebo-controlled, Randomized, Crossover, Multicenter Study of Solriamfetol in Improving Cognitive Function in Participants With Excessive Daytime Sleepiness Associated With Obstructive Sleep Apnea Plus Impaired Cognitive Function
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of study JZP110-405 is to determine whether solriamfetol is effective at improving cognitive function in participants with excessive daytime sleepiness (EDS) associated with obstructive sleep apnea (OSA) plus impaired cognitive function.
Study identification
- NCT ID
- NCT04789174
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 59 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 17, 2021 (Actual)
- Primary completion
- Sep 19, 2022 (Actual)
- Completion
- Sep 19, 2022 (Actual)
- Last update posted
- Jan 26, 2026
2021 – 2022
United States locations
- U.S. sites
- 15
- U.S. states
- 11
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Southern California Institute for Respiratory Disease | Los Angeles | California | 90048 | — |
| SDS Clinical Trials, Inc | Santa Ana | California | 92705 | — |
| Clinical Neuroscience Solutions, Inc | Jacksonville | Florida | 32256 | — |
| NeuroTrials Research Inc | Atlanta | Georgia | 30328 | — |
| The Neurological Center of north Georgia. | Gainesville | Georgia | 30501 | — |
| The Center for Sleep & Wake Disorders | Chevy Chase | Maryland | 20815 | — |
| Henry Ford Health System | Novi | Michigan | 48377 | — |
| Sleep Medicine & Research Center | Chesterfield | Missouri | 63017 | — |
| Advanced Respiratory and Sleep Medicine, PLLC | Huntersville | North Carolina | 28078 | — |
| CTI-Clinical Research Center | Cincinnati | Ohio | 45212 | — |
| Intrepid Research, LLC | Cincinnati | Ohio | 45245 | — |
| Bogan Sleep Consultants, LLC | Columbia | South Carolina | 29201 | — |
| FutureSearch Trials of Neuroglogy | Austin | Texas | 78731 | — |
| Sleep Therapy & Research Center | San Antonio | Texas | 78229 | — |
| Sleep and Performance Research Center | Spokane | Washington | 99202 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 13 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04789174, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 26, 2026 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04789174 live on ClinicalTrials.gov.