ClinicalTrials.gov record
Completed Phase 4 Interventional Results available

Solriamfetol's Effect on Cognitive Health in Apnea Participants During a Randomized Placebo-controlled Study

ClinicalTrials.gov ID: NCT04789174

Public ClinicalTrials.gov record NCT04789174. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 18, 2026, 10:34 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Solriamfetol's Effect on Cognitive Health in Apnea Participants During a Randomized Placebo-controlled Study (SHARP): a 5-Week Double-blind, Placebo-controlled, Randomized, Crossover, Multicenter Study of Solriamfetol in Improving Cognitive Function in Participants With Excessive Daytime Sleepiness Associated With Obstructive Sleep Apnea Plus Impaired Cognitive Function

Study identification

NCT ID
NCT04789174
Recruitment status
Completed
Study type
Interventional
Phase
Phase 4
Lead sponsor
Axsome Therapeutics, Inc.
Industry
Enrollment
59 participants

Conditions and interventions

Interventions

  • Placebo Drug
  • Solriamfetol Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 16, 2021
Primary completion
Sep 18, 2022
Completion
Sep 18, 2022
Last update posted
Jan 25, 2026

2021 – 2022

United States locations

U.S. sites
15
U.S. states
11
U.S. cities
14
Facility City State ZIP Site status
Southern California Institute for Respiratory Disease Los Angeles California 90048
SDS Clinical Trials, Inc Santa Ana California 92705
Clinical Neuroscience Solutions, Inc Jacksonville Florida 32256
NeuroTrials Research Inc Atlanta Georgia 30328
The Neurological Center of north Georgia. Gainesville Georgia 30501
The Center for Sleep & Wake Disorders Chevy Chase Maryland 20815
Henry Ford Health System Novi Michigan 48377
Sleep Medicine & Research Center Chesterfield Missouri 63017
Advanced Respiratory and Sleep Medicine, PLLC Huntersville North Carolina 28078
CTI-Clinical Research Center Cincinnati Ohio 45212
Intrepid Research, LLC Cincinnati Ohio 45245
Bogan Sleep Consultants, LLC Columbia South Carolina 29201
FutureSearch Trials of Neuroglogy Austin Texas 78731
Sleep Therapy & Research Center San Antonio Texas 78229
Sleep and Performance Research Center Spokane Washington 99202

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 13 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04789174, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 25, 2026 · Synced May 18, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04789174 live on ClinicalTrials.gov.

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