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Active, not recruiting Phase 2 Interventional

Study of Avelumab and/or Radiation Therapy in People With Advanced Merkel Cell Carcinoma

ClinicalTrials.gov ID: NCT04792073

Public ClinicalTrials.gov record NCT04792073. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 22, 2026, 4:37 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II Single-Arm Clinical Trial Assessing Comprehensive Ablative Radiation Therapy With Avelumab in Unresectable and Metastatic Merkel Cell Carcinoma (CARTA)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will test the use of comprehensive ablative radiation therapy (CART), with the immunotherapy drug avelumab, in people with Merkel cell carcinoma (MCC) that has progressed after treatment and cannot be removed with surgery. The study researchers want to find out if CART works well when combined with avelumab.

Study identification

NCT ID
NCT04792073
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Enrollment
18 participants

Conditions and interventions

Interventions

Drug · Radiation

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 8, 2021 (Actual)
Primary completion
Mar 2027 (Estimated)
Completion
Mar 2027 (Estimated)
Last update posted
Apr 7, 2026

2021 – 2027

United States locations

U.S. sites
7
U.S. states
2
U.S. cities
7
Facility City State ZIP Site status
Memorial Sloan Kettering Basking Ridge (All Protocol Activities) Basking Ridge New Jersey 07920 —
Memorial Sloan Kettering Monmouth (All Protocol Activities) Middletown New Jersey 07748 —
Memorial Sloan Kettering Bergen (All Protocol Activities) Montvale New Jersey 07645 —
Memorial Sloan Kettering Commack (All Protocol Activities) Commack New York 11725 —
Memorial Sloan Kettering Westchester (All Protocol Activities) Harrison New York 10604 —
Memorial Sloan Kettering Cancer Center (All Protocol Activities) New York New York 10065 —
Memorial Sloan Kettering Nassau (All Protocol Activities) Uniondale New York 11553 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04792073, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 7, 2026 · Synced Oct 22, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04792073 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →