A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)
Public ClinicalTrials.gov record NCT04811560. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2, First-in-Human Study of the Menin-KMT2A (MLL1) Inhibitor Bleximenib in Participants With Acute Leukemia (cAMeLot-1)
Study identification
- NCT ID
- NCT04811560
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Enrollment
- 420 participants
Conditions and interventions
Conditions
Interventions
- Bleximenib Drug
Drug
Eligibility (public fields only)
- Age range
- 2 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 18, 2021
- Primary completion
- Feb 25, 2027
- Completion
- Sep 21, 2030
- Last update posted
- May 7, 2026
2021 – 2030
United States locations
- U.S. sites
- 27
- U.S. states
- 17
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| City of Hope Phoenix | Goodyear | Arizona | 85338 | Terminated |
| City of Hope | Duarte | California | 91010 | Recruiting |
| University of California Irvine Medical Center | Orange | California | 92868 | Completed |
| University of California San Francisco | San Francisco | California | 94143 | Recruiting |
| UCSF Benioff Children's Hospital | San Francisco | California | 94158 | Recruiting |
| University of Chicago | Chicago | Illinois | 60637 | Recruiting |
| St Francis Hospital & Health Centers Indiana Blood and Marrow Transplantation | Indianapolis | Indiana | 46237 | Recruiting |
| Norton Cancer Institute | Louisville | Kentucky | 40207 | Completed |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | Recruiting |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02115 | Recruiting |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 2013 | Recruiting |
| Start Midwest | Grand Rapids | Michigan | 49546 | Recruiting |
| University of New Mexico | Albuquerque | New Mexico | 87131 | Recruiting |
| Roswell Park Comprehensive Cancer Center | Buffalo | New York | 14263 | Recruiting |
| NYU Langone Medical Center | New York | New York | 10016 | Recruiting |
| Montefiore Medical Center | The Bronx | New York | 10467 | Recruiting |
| Oregon Health And Science University | Portland | Oregon | 97239 | Recruiting |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | Recruiting |
| Maine Health | Providence | Rhode Island | 02903 | Recruiting |
| University of Tennessee Medical Center | Knoxville | Tennessee | 37920 | Recruiting |
| Baylor University Medical Center | Dallas | Texas | 75246 | Recruiting |
| Houston Methodist Hospital | Houston | Texas | 77030-2740 | Recruiting |
| MD Anderson | Houston | Texas | 77030 | Recruiting |
| San Antonio Methodist TX Transplant Physicians Group | San Antonio | Texas | 78229 | Recruiting |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | Recruiting |
| Swedish Cancer Institute | Seattle | Washington | 98104 | Recruiting |
| Medical College of WI at Froedtert | Milwaukee | Wisconsin | 53226 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 76 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04811560, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 7, 2026 · Synced May 10, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04811560 live on ClinicalTrials.gov.