A Study to Evaluate Safety and Immunogenicity of mRNA-1273 Vaccine to Prevent COVID-19 in Adult Organ Transplant Recipients and in Healthy Adult Participants
Public ClinicalTrials.gov record NCT04860297. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3b, Open-Label, Safety and Immunogenicity Study of SARS-CoV-2 mRNA-1273 Vaccine in Adult Solid Organ Transplant Recipients and Healthy Controls
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is an open-label study to evaluate the safety, reactogenicity, and immunogenicity of mRNA-1273 Severe Acute Respiratory Syndrome coronavirus (SARS-CoV-2) vaccine in adults with a kidney or liver solid organ transplant (SOT) and in healthy adult participants. The primary goal of the study is to evaluate the safety of mRNA-1273 and the serum antibody (Ab) responses obtained 28 days after the last dose of mRNA-1273.
Study identification
- NCT ID
- NCT04860297
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 234 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 15, 2021
- Primary completion
- May 21, 2023
- Completion
- May 21, 2023
- Last update posted
- Jun 17, 2024
2021 – 2023
United States locations
- U.S. sites
- 15
- U.S. states
- 12
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Aventiv Research Inc | Mesa | Arizona | 85206 | — |
| California Institute of Renal Research | San Diego | California | 92123 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06519 | — |
| Tampa General Medical Group | Tampa | Florida | 33606 | — |
| Piedmont Transplant Institute | Atlanta | Georgia | 30309 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| University of Massachusetts Medical School | Worcester | Massachusetts | 01655 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Northwell Health | Manhasset | New York | 11030 | — |
| Colombia University Medical Center | New York | New York | 10032 | — |
| University of Cincinnati | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic Hospital | Cleveland | Ohio | 44195 | — |
| Hospital of The University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Recently updated SARS-CoV-2 trials
Other public records listing SARS-CoV-2. Sorted by last update posted; newest first. Not a recommendation.
- NCT07743580: A Study of Secutrelvir in Participants With Coronavirus Disease 2019 (COVID-19) Who Are at High Risk for Progression to Severe Disease Not yet recruiting
- NCT07224490: Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease Recruiting
- NCT04568148: COVID-19 Biorepository Active, not recruiting
- NCT07266558: A Study to Evaluate the Efficacy and Safety of mRNA-1283 and mRNA-1273 in Participants 50 to 64 Years of Age Without High-Risk Conditions for Severe Coronavirus Disease 2019 (COVID-19) Active, not recruiting
- NCT06585241: A Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing Vaccine Formulations Recruiting
- NCT05876377: Use and Effectiveness of COVID-19 Vaccines Using State Vaccine Registries and Insurance Claims Data Active, not recruiting
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04860297, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 17, 2024 · Synced Sep 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04860297 live on ClinicalTrials.gov.