A Study to Test the Efficacy, Safety, and Tolerability of Bepranemab (UCB0107) in Patients With Mild Cognitive Impairment or Mild Alzheimer's Disease (AD)
Public ClinicalTrials.gov record NCT04867616. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Patient- and Investigator-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Bepranemab (UCB0107) in Study Participants With Prodromal to Mild Alzheimer's Disease (AD), Followed by an Open-Label Extension Period
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the study is to investigate the effect of bepranemab versus (vs) placebo on the Clinical Dementia Rating Scale Sum of Boxes (CDR-SB) up to Week 80 in study participants with prodromal or mild Alzheimer's Disease (AD).
Study identification
- NCT ID
- NCT04867616
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 466 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 9, 2021 (Actual)
- Primary completion
- May 24, 2024 (Actual)
- Completion
- Aug 1, 2025 (Actual)
- Last update posted
- Jul 24, 2026
2021 – 2025
United States locations
- U.S. sites
- 40
- U.S. states
- 13
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Ah0003 50428 | Fresno | California | 93710 | — |
| Ah0003 50431 | Fullerton | California | 92835 | — |
| Ah0003 50442 | Irvine | California | 92614 | — |
| Ah0003 50458 | Long Beach | California | 90807 | — |
| Ah0003 50450 | Palo Alto | California | 94303 | — |
| Ah0003 50452 | Pasadena | California | 91106 | — |
| Ah0003 50447 | San Diego | California | 92123 | — |
| Ah0003 50434 | Santa Ana | California | 92705 | — |
| Ah0003 50422 | New Haven | Connecticut | 06510 | — |
| Ah0003 50467 | New Haven | Connecticut | 06510 | — |
| Ah0003 50421 | Stamford | Connecticut | 06905 | — |
| Ah0003 50465 | Atlantis | Florida | 33462 | — |
| Ah0003 50449 | Aventura | Florida | 33180 | — |
| Ah0003 50435 | Boca Raton | Florida | 33487 | — |
| Ah0003 50430 | Delray Beach | Florida | 33445 | — |
| Ah0003 50429 | Fort Myers | Florida | 33912 | — |
| Ah0003 50436 | Hialeah | Florida | 33016 | — |
| Ah0003 50426 | Maitland | Florida | 32751 | — |
| Ah0003 50427 | Miami | Florida | 33125 | — |
| Ah0003 50478 | Naples | Florida | 34105 | — |
| Ah0003 50464 | Ocoee | Florida | 34761 | — |
| Ah0003 50438 | Pensacola | Florida | 32502 | — |
| Ah0003 50623 | Pensacola | Florida | 32503 | — |
| Ah0003 50457 | Port Orange | Florida | 32127 | — |
| Ah0003 50454 | Tampa | Florida | 33613 | — |
| Ah0003 50444 | West Palm Beach | Florida | 33407 | — |
| Ah0003 50476 | West Palm Beach | Florida | 33409 | — |
| Ah0003 50446 | Westchester | Florida | 33155 | — |
| Ah0003 50479 | Decatur | Georgia | 30033 | — |
| Ah0003 50445 | Braintree | Massachusetts | 02184 | — |
| Ah0003 50453 | Newton | Massachusetts | 02459 | — |
| Ah0003 50448 | Saint Paul | Minnesota | 55130 | — |
| Ah0003 50420 | Neptune City | New Jersey | 07753 | — |
| Ah0003 50451 | Cincinnati | Ohio | 45219 | — |
| Ah0003 50423 | East Providence | Rhode Island | 02914 | — |
| Ah0003 50455 | Cordova | Tennessee | 38018 | — |
| Ah0003 50380 | Houston | Texas | 77054 | — |
| Ah0003 50424 | Fairfax | Virginia | 22031 | — |
| Ah0003 50432 | Norfolk | Virginia | 23507 | — |
| Ah0003 50440 | Bellevue | Washington | 98007 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 63 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04867616, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 24, 2026 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04867616 live on ClinicalTrials.gov.