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Recruiting Phase 1Phase 2 Interventional

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

ClinicalTrials.gov ID: NCT04870944

Public ClinicalTrials.gov record NCT04870944. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 6, 2026, 8:58 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1/2 Trial of CBL0137 (NSC# 825802) in Patients With Relapsed or Refractory Solid Tumors Including CNS Tumors and Lymphoma

Study identification

NCT ID
NCT04870944
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Children's Oncology Group
Network
Enrollment
63 participants

Conditions and interventions

Interventions

  • Biospecimen Collection Procedure
  • Bone Marrow Aspirate Procedure
  • Bone Marrow Biopsy Procedure
  • Echocardiography Test Procedure
  • FACT Complex-targeting Curaxin CBL0137 Drug

Procedure · Drug

Eligibility (public fields only)

Age range
12 Months to 21 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 27, 2022
Primary completion
Dec 30, 2026
Completion
Dec 30, 2026
Last update posted
May 4, 2026

2022 – 2026

United States locations

U.S. sites
34
U.S. states
24
U.S. cities
32
Facility City State ZIP Site status
Children's Hospital of Alabama Birmingham Alabama 35233 Recruiting
Phoenix Childrens Hospital Phoenix Arizona 85016 Recruiting
Children's Hospital Los Angeles Los Angeles California 90027 Recruiting
Children's Hospital of Orange County Orange California 92868 Recruiting
UCSF Medical Center-Mission Bay San Francisco California 94158 Recruiting
Children's Hospital Colorado Aurora Colorado 80045 Recruiting
Children's National Medical Center Washington D.C. District of Columbia 20010 Recruiting
Johns Hopkins All Children's Hospital St. Petersburg Florida 33701 Recruiting
Children's Healthcare of Atlanta - Arthur M Blank Hospital Atlanta Georgia 30329 Recruiting
Lurie Children's Hospital-Chicago Chicago Illinois 60611 Recruiting
University of Chicago Comprehensive Cancer Center Chicago Illinois 60637 Recruiting
Riley Hospital for Children Indianapolis Indiana 46202 Recruiting
Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore Maryland 21287 Recruiting
Dana-Farber Cancer Institute Boston Massachusetts 02215 Recruiting
C S Mott Children's Hospital Ann Arbor Michigan 48109 Recruiting
University of Minnesota/Masonic Cancer Center Minneapolis Minnesota 55455 Recruiting
Children's Mercy Hospitals and Clinics Kansas City Missouri 64108 Recruiting
Washington University School of Medicine St Louis Missouri 63110 Recruiting
Roswell Park Cancer Institute Buffalo New York 14263 Recruiting
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center New York New York 10032 Recruiting
Memorial Sloan Kettering Cancer Center New York New York 10065 Recruiting
New York Medical College Valhalla New York 10595 Recruiting
Duke University Medical Center Durham North Carolina 27710 Recruiting
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229 Recruiting
Oregon Health and Science University Portland Oregon 97239 Recruiting
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104 Recruiting
Children's Hospital of Pittsburgh of UPMC Pittsburgh Pennsylvania 15224 Recruiting
Saint Jude Children's Research Hospital Memphis Tennessee 38105 Recruiting
UT Southwestern/Simmons Cancer Center-Dallas Dallas Texas 75390 Recruiting
Cook Children's Medical Center Fort Worth Texas 76104 Recruiting
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center Houston Texas 77030 Recruiting
Primary Children's Hospital Salt Lake City Utah 84113 Recruiting
Seattle Children's Hospital Seattle Washington 98105 Recruiting
Children's Hospital of Wisconsin Milwaukee Wisconsin 53226 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04870944, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 4, 2026 · Synced May 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04870944 live on ClinicalTrials.gov.

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