RegoNivo vs Standard of Care Chemotherapy in AGOC
Public ClinicalTrials.gov record NCT04879368. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomised Phase III Open Label Study of Regorafenib + Nivolumab vs Standard Chemotherapy in Refractory Advanced Gastro-Oesophageal Cancer (AGOC)
Study identification
- NCT ID
- NCT04879368
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Australasian Gastro-Intestinal Trials Group
- Network
- Enrollment
- 450 participants
Conditions and interventions
Conditions
Interventions
- Docetaxel Drug
- Irinotecan Drug
- Nivolumab Biological
- Paclitaxel Drug
- Regorafenib Drug
- Trifluridine/Tipracil Drug
Drug · Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2021
- Primary completion
- Jul 8, 2025
- Completion
- May 31, 2026
- Last update posted
- Jul 16, 2025
2021 – 2026
United States locations
- U.S. sites
- 6
- U.S. states
- 6
- U.S. cities
- 6
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic Arizona | Scottsdale | Arizona | 85054 | — |
| USC Norris | Los Angeles | California | 90001 | — |
| Siouxland Regional Cancer Center | Sioux City | Iowa | 51101 | — |
| St Elizabeth Healthcare | Edgewood | Kentucky | 41017 | — |
| Monument Health Rapid City Hospital | Rapid City | South Dakota | 57701 | — |
| Fred Hutchinson Cancer Research Centre - South Lake Union Clinic | Seattle | Washington | 98109 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 88 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04879368, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 16, 2025 · Synced May 10, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04879368 live on ClinicalTrials.gov.