ClinicalTrials.gov record
Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 18 to 75 Years of Age Treated With Subcutaneous (SC) Injections of ABBV-154 for Moderately to Severely Active Rheumatoid Arthritis (RA)
ClinicalTrials.gov ID: NCT04888585
Public ClinicalTrials.gov record NCT04888585. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 14, 2026, 9:20 PM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of ABBV-154 in Subjects With Moderately to Severely Active Rheumatoid Arthritis With Inadequate Response to Biologic and/or Targeted Synthetic Disease-Modifying Anti-Rheumatic Drugs (b/tsDMARDs)
Study identification
- NCT ID
- NCT04888585
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- AbbVie
- Industry
- Enrollment
- 473 participants
Conditions and interventions
Conditions
Interventions
- ABBV-154 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 22, 2021
- Primary completion
- Aug 24, 2022
- Completion
- Aug 3, 2023
- Last update posted
- Oct 7, 2024
2021 – 2023
United States locations
- U.S. sites
- 101
- U.S. states
- 32
- U.S. cities
- 92
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Elite Clinical Studies, LLC /ID# 228227 | Phoenix | Arizona | 85018 | — |
| Arthritis and Rheumatism Associates /ID# 228201 | Jonesboro | Arkansas | 72401-6251 | — |
| Providence Medical Foundation /ID# 228104 | Fullerton | California | 92835 | — |
| Care Access Research, Huntington Beach /ID# 228163 | Huntington Beach | California | 92648 | — |
| Purushotham & Akther Kotha MD, Inc /ID# 228120 | La Mesa | California | 91942 | — |
| Arthritis & Osteo Medical Ctr /ID# 228239 | La Palma | California | 90623-1728 | — |
| Pacific Arthritis Care Center - Los Angeles /ID# 229330 | Los Angeles | California | 90045-6200 | — |
| California Medical Research Associates /ID# 230131 | Northridge | California | 91324 | — |
| Arthritis Care And Research Center ACRC /ID# 230099 | Poway | California | 92064 | — |
| East Bay Rheumatology Medical /ID# 228099 | San Leandro | California | 94578 | — |
| Millennium Clinical Trials /ID# 230618 | Thousand Oaks | California | 91360-3951 | — |
| The Lundquist Institute at Harbor-UCLA Medical Center /ID# 228241 | Torrance | California | 90502 | — |
| Medvin Clinical Research /ID# 228181 | Tujunga | California | 91042-2706 | — |
| Inland Rheum & Osteo Med Grp /ID# 228204 | Upland | California | 91786 | — |
| Comprehensive Rheumatology Center /ID# 230132 | Woodland Hills | California | 91364 | — |
| Denver Arthritis Clinic /ID# 228172 | Denver | Colorado | 80230 | — |
| New England Research Associates, LLC /ID# 230127 | Bridgeport | Connecticut | 06606-1827 | — |
| Stamford Therapeutics Consorti /ID# 229214 | Stamford | Connecticut | 06905 | — |
| Delaware Arthritis /ID# 229413 | Lewes | Delaware | 19958 | — |
| Rheumatology Associates of South Florida (RASF) - Clinical Research /ID# 228229 | Boca Raton | Florida | 33486 | — |
| Bay Area Arthritis and Osteo /ID# 228075 | Brandon | Florida | 33511 | — |
| Clinical Research of West Florida, Inc /ID# 228128 | Clearwater | Florida | 33765 | — |
| International Medical Research /ID# 228069 | Daytona Beach | Florida | 32117 | — |
| Omega Research Debary, LLC /ID# 228293 | DeBary | Florida | 32713-2260 | — |
| Neoclinical Research /ID# 228753 | Hialeah | Florida | 33016-1897 | — |
| University of Florida /ID# 228242 | Jacksonville | Florida | 32209 | — |
| Lakes Research, LLC /ID# 228665 | Miami | Florida | 33014 | — |
| University of Miami /ID# 228737 | Miami | Florida | 33136 | — |
| Suncoast Clinical Research /ID# 228237 | New Port Richey | Florida | 34652 | — |
| Omega Research Group /ID# 229966 | Orlando | Florida | 32808 | — |
| HMD Research LLC /ID# 228185 | Orlando | Florida | 32819 | — |
| Millennium Research /ID# 228183 | Ormond Beach | Florida | 32174 | — |
| Arthritis Center, Inc. /ID# 228209 | Palm Harbor | Florida | 34684 | — |
| BayCare Medical Group /ID# 228289 | St. Petersburg | Florida | 33705 | — |
| West Broward Rheumatology Associates /ID# 228603 | Tamarac | Florida | 33321 | — |
| Clinical Research of West Florida - Tampa /ID# 228186 | Tampa | Florida | 33606-1246 | — |
| Conquest Research /ID# 230560 | Winter Park | Florida | 32789 | — |
| Florida Medical Clinic /ID# 228236 | Zephyrhills | Florida | 33542 | — |
| Arthritis and Rheumatology /ID# 228743 | Atlanta | Georgia | 30342 | — |
| Jefrey D. Lieberman, MD, P.C. /ID# 230129 | Decatur | Georgia | 30033 | — |
| Arthritis Center of North GA /ID# 228769 | Gainesville | Georgia | 30501 | — |
| Atlanta Research Center for Rheumatology /ID# 230430 | Marietta | Georgia | 20060 | — |
| Great Lakes Clinical Trials /ID# 228699 | Chicago | Illinois | 60640 | — |
| Greater Chicago Specialty Physicians /ID# 228282 | Schaumburg | Illinois | 60195-3106 | — |
| Clinic of Robert Hozman/Clinical Investigation Specialists /ID# 228174 | Skokie | Illinois | 60076 | — |
| Springfield Clinic /ID# 228124 | Springfield | Illinois | 62702-3749 | — |
| Beacon Medical Group Clinical Research /ID# 229153 | Granger | Indiana | 46530 | — |
| University of Iowa Hospitals and Clinics /ID# 229217 | Iowa City | Iowa | 52242 | — |
| Four Rivers Clinical Research /ID# 230109 | Paducah | Kentucky | 42001 | — |
| The Arthritis & Diabetes Clinic, Inc. /ID# 228221 | Monroe | Louisiana | 71203 | — |
| Klein and Associates MD /ID# 230145 | Cumberland | Maryland | 21502 | — |
| Klein and Associates MD - Hagerstown /ID# 230143 | Hagerstown | Maryland | 21742 | — |
| The Center for Rheumatology and Bone Research /ID# 228617 | Wheaton | Maryland | 20902 | — |
| AA Medical Research Center - Grand Blanc /ID# 228604 | Grand Blanc | Michigan | 48439 | — |
| Advanced Rheumatology, PC /ID# 228684 | Lansing | Michigan | 48910 | — |
| June DO, PC /ID# 229838 | Lansing | Michigan | 48911 | — |
| Arthritis Associates /ID# 230188 | Hattiesburg | Mississippi | 39402 | — |
| Rheumatology Consultants - Clinical Research /ID# 229208 | Tupelo | Mississippi | 38801-4949 | — |
| Clayton Medical Associates, P.C. dba Saint Louis Rheumatology /ID# 228283 | St Louis | Missouri | 63119-3845 | — |
| West County Rheumatology /ID# 228102 | St Louis | Missouri | 63131-1703 | — |
| Logan Health Research /ID# 228273 | Kalispell | Montana | 59901 | — |
| Advanced Biomedical Research of America /ID# 228596 | Las Vegas | Nevada | 89123 | — |
| Innovative Health Research /ID# 229209 | Las Vegas | Nevada | 89128 | — |
| Arthritis and Osteoporosis Associates /ID# 229418 | Freehold | New Jersey | 07728-8307 | — |
| Arthritis Rheumatic and Back Disease Associates. P.A. /ID# 228602 | Voorhees Township | New Jersey | 08043 | — |
| Albuquerque Center For Rheumatology /ID# 228709 | Albuquerque | New Mexico | 87102 | — |
| Albuquerque Clinical Trials, Inc /ID# 228925 | Albuquerque | New Mexico | 87102 | — |
| Arthritis and Osteo Assoc /ID# 228662 | Las Cruces | New Mexico | 88011 | — |
| Buffalo Rheumatology and Medicine - Orchard Park /ID# 228710 | Orchard Park | New York | 14127 | — |
| St. Lawrence Health System /ID# 229508 | Potsdam | New York | 13676 | — |
| DJL Clinical Research, PLLC /ID# 230133 | Charlotte | North Carolina | 28211 | — |
| Cape Fear Arthritis Care /ID# 228747 | Leland | North Carolina | 28451 | — |
| PMG Research of Salisbury /ID# 230627 | Salisbury | North Carolina | 28144 | — |
| Trinity Health Med Arts Clinic /ID# 228202 | Minot | North Dakota | 58701 | — |
| University of Cincinnati /ID# 229212 | Cincinnati | Ohio | 45267-0585 | — |
| Paramount Medical Research Con /ID# 228254 | Middleburg Heights | Ohio | 44130 | — |
| Arthritis Assoc of NW Ohio /ID# 228936 | Toledo | Ohio | 43606 | — |
| Arthritis and Rheumatology Center of Oklahoma /ID# 228975 | Oklahoma City | Oklahoma | 73102 | — |
| Rheumatology Associates of Oklahoma /ID# 228701 | Oklahoma City | Oklahoma | 73116-7226 | — |
| Advanced Rheumatology & Arthritis Wellness Center /ID# 228608 | Cranberry Township | Pennsylvania | 16066 | — |
| Altoona Ctr Clinical Res /ID# 230058 | Duncansville | Pennsylvania | 16635 | — |
| Arthritis Group /ID# 229777 | Philadelphia | Pennsylvania | 19152 | — |
| PA Regional Center for Arthritis and Osteoporosis Research /ID# 228742 | Wyomissing | Pennsylvania | 19610 | — |
| Columbia Arthritis Center /ID# 228705 | Columbia | South Carolina | 29204 | — |
| West Tennessee Research Institute /ID# 228257 | Jackson | Tennessee | 38305 | — |
| Arthritis and Rheumatology Research Institute, PLLC /ID# 228937 | Allen | Texas | 75013-6147 | — |
| Allen Arthritis /ID# 228712 | Allen | Texas | 75013 | — |
| Trinity Universal Research Associates - Carrollton /ID# 230104 | Carrollton | Texas | 75007 | — |
| Adriana Pop-Moody MD Clinic PA /ID# 230062 | Corpus Christi | Texas | 78404 | — |
| West Texas Clinical Research /ID# 228276 | Lubbock | Texas | 79424 | — |
| P&I Clinical Research /ID# 230183 | Lufkin | Texas | 75904-3132 | — |
| SW Rheumatology Res. LLC /ID# 228088 | Mesquite | Texas | 75150 | — |
| Trinity Universal Research Associates, Inc /ID# 228238 | Plano | Texas | 75024-5283 | — |
| Epic Medical Research /ID# 228097 | Red Oak | Texas | 75154-3981 | — |
| Sun Research Institute /ID# 228768 | San Antonio | Texas | 78215 | — |
| Advanced Rheumatology of Houston /ID# 228170 | The Woodlands | Texas | 77382 | — |
| DM Clinical Research - Tomball /ID# 228112 | Tomball | Texas | 77375 | — |
| Rheumatology Clinic of Houston /ID# 228178 | Tomball | Texas | 77377 | — |
| Arthritis & Osteoporosis Clinic /ID# 228736 | Waco | Texas | 76710 | — |
| Tidewater Physicians Medical Center /ID# 230130 | Newport News | Virginia | 23606-4434 | — |
| Arthritis Northwest, PLLC /ID# 228275 | Spokane | Washington | 99204-2302 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 119 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04888585, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 7, 2024 · Synced May 14, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04888585 live on ClinicalTrials.gov.