Study to Evaluate the Efficacy and Safety of TT-00420 (Tinengotinib) in Cholangiocarcinoma
Public ClinicalTrials.gov record NCT04919642. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Open Label, Multicenter Study to Evaluate the Efficacy and Safety of TT-00420 (Tinengotinib) Tablet in Adult Patients With Advanced Cholangiocarcinoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is an open-label, multicenter study to evaluate the efficacy and safety of TT-00420 tablet in adult patients with advanced cholangiocarcinoma.
Study identification
- NCT ID
- NCT04919642
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 55 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 7, 2021 (Actual)
- Primary completion
- Feb 28, 2024 (Actual)
- Completion
- Feb 28, 2024 (Actual)
- Last update posted
- Jun 25, 2024
2021 – 2024
United States locations
- U.S. sites
- 32
- U.S. states
- 18
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Providence Cancer Center | Anchorage | Alaska | 99508 | — |
| City of Hope | Duarte | California | 91010 | — |
| University of California, Los Angeles, School of Medicine | Santa Monica | California | 90404 | — |
| USO Oncology Network- Rocky Mountain Cancer Centers | Denver | Colorado | 80218-1237 | — |
| Mount Sinai Medical Center | Miami Beach | Florida | 33140 | — |
| University of Chicago Medical Center - Duchossis Center for Advanced Medicine | Chicago | Illinois | 60637-1426 | — |
| University of Maryland - Marlene and Stewart Greenebaum Cancer Center | Baltimore | Maryland | 21250 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Health Center | Detroit | Michigan | 48202 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Comprehensive Cancer Center of Nevada | Las Vegas | Nevada | 89169 | — |
| Summit Medical Group - Florham Park Campus | Florham Park | New Jersey | 07932 | — |
| Roswell Park Comprehensive Cancer Center | Buffalo | New York | 14203 | — |
| Ruttenberg Treatment Center - Mount Sinai | New York | New York | 10029 | — |
| USOR Oncology Network- New York Oncology | New York | New York | 12208 | — |
| Stony Brook University - Long Island Cancer Center | Stony Brook | New York | 11794 | — |
| University of Cincinnati Cancer Institute | Cincinnati | Ohio | 45219 | — |
| University Hospitals Seidman Cancer Center | Cleveland | Ohio | 44106 | — |
| USO Oncology Network-Northwest Cancer Specialists, P.C. | Portland | Oregon | 97227 | — |
| Medical College of South Carolina | Charleston | South Carolina | 29425 | — |
| The University of Tennessee Medical Center | Knoxville | Tennessee | 37920 | — |
| Sarah Cannon Research Institute at Tennessee Oncology | Nashville | Tennessee | 37203 | — |
| Methodist Dallas Medical Center | Dallas | Texas | 75203 | — |
| Parkland Health & Hospital System | Dallas | Texas | 75235 | — |
| University of Texas Southwestern Harold C. Simmons Comprehensive Cancer Center | Dallas | Texas | 75235 | — |
| Houston Methodist Hospital - Outpatient Center | Houston | Texas | 77030 | — |
| UT MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| USO Oncology Network-Texas Oncology | Tyler | Texas | 75702-8363 | — |
| USO Oncology Network-Virginia Oncology Associates - Brock Cancer Center - Norfolk | Norfolk | Virginia | 23502-2824 | — |
| USO Oncology Network-Oncology and Hematology Associates of Southwest Virginia, Inc. | Roanoke | Virginia | 24014 | — |
| University of Wisconsin School of Medicine and Public Health | Madison | Wisconsin | 53705 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04919642, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 25, 2024 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04919642 live on ClinicalTrials.gov.