Taletrectinib Phase 2 Global Study in ROS1 Positive NSCLC
Public ClinicalTrials.gov record NCT04919811. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Single-Arm, Open-Label, Multicenter Phase 2 Study to Evaluate the Efficacy and Safety of Taletrectinib in Patients With Advanced or Metastatic ROS1 Positive NSCLC and Other Solid Tumors
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of the study is to evaluate safety and efficacy of taletrectinib (also known as AB-106 or DS-6051b) monotherapy in the treatment of advanced NSCLC.
Study identification
- NCT ID
- NCT04919811
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 217 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 1, 2021 (Actual)
- Primary completion
- Jun 11, 2025 (Actual)
- Completion
- Dec 2027 (Estimated)
- Last update posted
- Jan 7, 2026
2021 – 2027
United States locations
- U.S. sites
- 20
- U.S. states
- 9
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Beverly Hills Cancer Center | Beverly Hills | California | 90211 | — |
| The Oncology Institute of Hope and Innovation | Glendale | California | 91204 | — |
| Moores Cancer Center at UC San Diego | La Jolla | California | 92037 | — |
| Keck Medicine of University of Southern California | Los Angeles | California | 90089 | — |
| UCI Medical Center | Orange | California | 92868 | — |
| Ventura County Hematology-Oncology Specialists | Oxnard | California | 93030 | — |
| SCRI - Florida Cancer Specialists South | Fort Meyers | Florida | 33901 | — |
| Memorial Cancer Institute at Memorial Hospital East | Hollywood | Florida | 33021 | — |
| Cancer Specialists of North Florida | Jacksonville | Florida | 92868 | — |
| Memorial Cancer Institute at Memorial Hospital West | Pembroke Pines | Florida | 33028 | — |
| SCRI - Hematology Oncology Clinic | Baton Rouge | Louisiana | 70809 | — |
| Mayo Clinic | Rochester | Minnesota | 55902 | — |
| Center for Cancer Research | Brick | New Jersey | 08724 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| SCRI - Tennessee Oncology | Nashville | Tennessee | 37203 | — |
| Texas Oncology, P.A. | Dallas | Texas | 75246 | — |
| Renovatio Clinical | El Paso | Texas | 19915 | — |
| MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Renovatio Clinical | The Woodlands | Texas | 77380 | — |
| Northwest Medical Specialties, PLLC | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 57 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04919811, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 7, 2026 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04919811 live on ClinicalTrials.gov.