A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

ClinicalTrials.gov ID: NCT04928846

Public ClinicalTrials.gov record NCT04928846. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Apr 29, 2026, 9:04 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3 Open-Label, Randomized, Controlled, Global Study of Telisotuzumab Vedotin (ABBV-399) Versus Docetaxel in Subjects With Previously Treated c-Met Overexpressing, EGFR Wildtype, Locally Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer

Study identification

NCT ID: NCT04928846
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: AbbVie; Industry
Enrollment: 698 participants

Conditions and interventions

Conditions

Non Small Cell Lung Cancer

Interventions

Docetaxel Drug
Telisotuzumab Vedotin Biological

Drug · Biological

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Mar 24, 2022
Primary completion: Feb 29, 2028
Completion: Feb 29, 2028
Last update posted: Apr 13, 2026

2022 – 2028

United States locations

U.S. sites: 50
U.S. states: 29
U.S. cities: 48

Facility	City	State	ZIP	Site status
University of Alabama at Birmingham - Main /ID# 247074	Birmingham	Alabama	35233	Active, not recruiting
Ironwood Cancer & Res Ctr /ID# 262446	Chandler	Arizona	85224-5665	Active, not recruiting
Mayo Clinic Arizona /ID# 255858	Phoenix	Arizona	85054-4504	Recruiting
Onvida Health Yuma Medical Center /ID# 253625	Yuma	Arizona	85364	Completed
City of Hope /ID# 243157	Duarte	California	91010	Recruiting
City Of Hope - Seacliff /ID# 263143	Huntington Beach	California	92648	Recruiting
City of Hope - Orange County Lennar Foundation Cancer Center /ID# 263144	Irvine	California	92618	Recruiting
City Of Hope - Antelope Valley /ID# 263138	Lancaster	California	93534	Recruiting
The Oncology Institute Of Hope & Innovation -East Los A /ID# 239774	Los Angeles	California	90033	Completed
University of California, Los Angeles /ID# 253954	Los Angeles	California	90095	Recruiting
Eisenhower Medical Center /ID# 233189	Rancho Mirage	California	92270-3221	Recruiting
Mayo Clinic Hospital Jacksonville /ID# 254688	Jacksonville	Florida	32224	Active, not recruiting
Ocala Oncology Florida Cancer Affiliates - Main /ID# 234228	Ocala	Florida	34474-4445	Active, not recruiting
BRCR Medical Center Inc /ID# 262344	Tamarac	Florida	33321-2919	Completed
Memorial University Medical Center /ID# 264081	Savannah	Georgia	31404	Completed
Kaiser Permanente Moanalua Medical Center /ID# 238363	Honolulu	Hawaii	96819-1469	Recruiting
Edward-Elmhurst Cancer Center /ID# 238552	Elmhurst	Illinois	60126	Active, not recruiting
Springfield Clinic - First /ID# 262290	Springfield	Illinois	62702	Active, not recruiting
Goshen Center for Cancer Care /ID# 257734	Goshen	Indiana	46526	Completed
Investigative Clinical Research of Indiana - Indianapolis /ID# 260468	Indianapolis	Indiana	46260	Recruiting
Baptist Health Lexington /ID# 252769	Lexington	Kentucky	40503	Recruiting
Dana-Farber Cancer Institute /ID# 247132	Boston	Massachusetts	02215	Active, not recruiting
Trinity Health St. Joseph Mercy Ann Arbor /ID# 232190	Ypsilanti	Michigan	48197-1051	Completed
Mayo Clinic - Rochester /ID# 252052	Rochester	Minnesota	55905-0001	Active, not recruiting
Hattiesburg Clinic /ID# 248033	Hattiesburg	Mississippi	39401	Recruiting
St. Luke's Hospital - Chesterfield /ID# 251688	Chesterfield	Missouri	63017	Recruiting
St. Lukes Hosp. of Kansas City /ID# 259940	Kansas City	Missouri	64111	Recruiting
Alliance for Multispecialty Research (AMR) - Kansas City /ID# 247567	Kansas City	Missouri	64114-4859	Completed
Hulston Cancer Center /ID# 232226	Springfield	Missouri	65807-5287	Recruiting
Saint Louis University Cancer Center /ID# 260722	St Louis	Missouri	63110-2539	Completed
Intermountain Health St. Vincent Regional Hospital - Cancer Centers of Montana /ID# 253147	Billings	Montana	59102	Active, not recruiting
Nebraska Hematology Oncology /ID# 257710	Lincoln	Nebraska	68506	Recruiting
Renown Medical Group - Oncology/Hematology /ID# 247942	Reno	Nevada	89502-1464	Recruiting
Astera Cancer Care /ID# 257753	East Brunswick	New Jersey	08816-4096	Active, not recruiting
San Juan Oncology Associates /ID# 244387	Farmington	New Mexico	87401	Active, not recruiting
Maimonides Medical Center /ID# 240783	Brooklyn	New York	11219	Active, not recruiting
Northwell Health - Monter Cancer Center /ID# 247081	Lake Success	New York	11042	Recruiting
AdventHealth Hendersonville /ID# 265349	Hendersonville	North Carolina	28792	Recruiting
FirstHealth of the Carolinas- Speciality Center /ID# 241279	Pinehurst	North Carolina	28374	Active, not recruiting
Genesis Cancer Care Center /ID# 239190	Zanesville	Ohio	43701-1406	Active, not recruiting
Cancer Care Associates Of York /ID# 266143	York	Pennsylvania	17403	Active, not recruiting
Medical University of South Carolina /ID# 251383	Charleston	South Carolina	29425	Recruiting
St Francis Cancer Center /ID# 243596	Greenville	South Carolina	29607-5253	Active, not recruiting
Avera Cancer Institute - Aberdeen /ID# 257759	Aberdeen	South Dakota	57401	Active, not recruiting
Avera Cancer Institute /ID# 239635	Sioux Falls	South Dakota	57105	Active, not recruiting
Duplicate_Memphis VA Medical Center /ID# 263250	Memphis	Tennessee	38104	Completed
Dell Seton Medical Center /ID# 247016	Austin	Texas	78701	Active, not recruiting
Community Cancer Trials of Utah - South Ogden /ID# 262829	Ogden	Utah	84405-7194	Recruiting
Valley Medical Center /ID# 253950	Renton	Washington	98055-5738	Recruiting
Medical Oncology Associates /ID# 247003	Spokane	Washington	99208	Completed

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 266 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT04928846, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 13, 2026 · Synced Apr 29, 2026

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The complete protocol, eligibility criteria, and contact information for NCT04928846 live on ClinicalTrials.gov.

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