A Study to Evaluate the Safety, Tolerability, and Blood Levels of ACU193 in Participants With MCI or Mild AD
Public ClinicalTrials.gov record NCT04931459. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1 Placebo-Controlled, Single- and Multiple-Dose Study of the Safety, Tolerability, and Pharmacokinetics of Intravenous ACU193 in Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This Phase 1 study is a single ascending dose (SAD) and multiple ascending dose (MAD), placebo-controlled study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of intravenous ACU193 when administered to participants diagnosed with Mild Cognitive Impairment (MCI) or Mild Dementia due to Alzheimer's disease (AD).
Study identification
- NCT ID
- NCT04931459
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 65 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 55 Years to 90 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 21, 2021 (Actual)
- Primary completion
- Jun 12, 2023 (Actual)
- Completion
- Jun 12, 2023 (Actual)
- Last update posted
- Jul 19, 2023
2021 – 2023
United States locations
- U.S. sites
- 17
- U.S. states
- 9
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Endpoints | Scottsdale | Arizona | 85258 | — |
| Orange County Research Institute | Anaheim | California | 92801 | — |
| Hoag Hospital Newport Beach | Newport Beach | California | 92663 | — |
| Velocity Clinical Research | Hallandale | Florida | 33009 | — |
| Charter Research | Lady Lake | Florida | 32159 | — |
| Columbus Clinical Services | Miami | Florida | 33125 | — |
| Combined Research Orlando Phase I-IV | Orlando | Florida | 32807 | — |
| Progressive Medical Research | Port Orange | Florida | 32321 | — |
| Santos Research Center | Tampa | Florida | 33615 | — |
| Atlanta Center for Medical Research | Atlanta | Georgia | 30331 | — |
| iResearch Atlanta | Decatur | Georgia | 30030 | — |
| Advanced Memory Research Institute of NJ | Toms River | New Jersey | 08755 | — |
| Columbia University | New York | New York | 10032 | — |
| AMC Research | Matthews | North Carolina | 28105 | — |
| Abington Neurological Associates | Abington | Pennsylvania | 19001 | — |
| Kerwin Medical Center | Dallas | Texas | 75231 | — |
| Clinical Trials Network | Houston | Texas | 77074 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04931459, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 19, 2023 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04931459 live on ClinicalTrials.gov.