A Study of 177Lu-FAP-2286 in Advanced Solid Tumors
Public ClinicalTrials.gov record NCT04939610. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
LuMIERE: A Phase 1/2, Multicenter, Open-label, Non-randomized Study to Investigate Safety and Tolerability, Pharmacokinetics, Dosimetry, and Preliminary Activity of 177Lu-FAP-2286 in Patients With an Advanced Solid Tumor
Study identification
- NCT ID
- NCT04939610
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Enrollment
- 222 participants
Conditions and interventions
Conditions
Interventions
- 177Lu-FAP-2286 Drug
- 68Ga-FAP-2286 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 29, 2021
- Primary completion
- Jun 29, 2026
- Completion
- Jun 29, 2028
- Last update posted
- Apr 22, 2026
2021 – 2028
United States locations
- U.S. sites
- 20
- U.S. states
- 15
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UAB Comprehensive Cancer Center | Birmingham | Alabama | 35233 | Recruiting |
| City of Hope | Duarte | California | 91010 | Recruiting |
| Hoag Hospital Irvine | Irvine | California | 92618 | Recruiting |
| University of California Los Angeles (UCLA) | Los Angeles | California | 90095 | Recruiting |
| UCSF Medical Center | San Francisco | California | 94158 | Recruiting |
| Mayo Clinic | Jacksonville | Florida | 32224 | Recruiting |
| University of Miami Hospital and Clinics | Miami | Florida | 33136 | Recruiting |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | Recruiting |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | Recruiting |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | Recruiting |
| Mayo Clinic | Rochester | Minnesota | 55905 | Recruiting |
| Saint Louis University Hospital | St Louis | Missouri | 63110-2539 | Recruiting |
| Columbia University Medical Center | New York | New York | 10032 | Recruiting |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | Recruiting |
| UNC Hospitals | Chapel Hill | North Carolina | 27514 | Recruiting |
| Oregon Health and Science University | Portland | Oregon | 97239-3098 | Recruiting |
| UPMC Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | Recruiting |
| University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| Univ of Utah, Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | Recruiting |
| Fred Hutchinson Cancer Center | Seattle | Washington | 98109-1023 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04939610, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 22, 2026 · Synced Apr 26, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04939610 live on ClinicalTrials.gov.