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Terminated Phase 2 Interventional Results available

A Trial of the Safety, Tolerability, and Pharmacodynamics of CVL-871 in Subjects With Dementia-Related Apathy

ClinicalTrials.gov ID: NCT04958031

Public ClinicalTrials.gov record NCT04958031. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 15, 2026, 9:29 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo-Controlled Trial To Evaluate the Safety, Tolerability, and Pharmacodynamics of CVL-871 in Subjects With Dementia-Related Apathy

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine whether CVL-871 is safe and tolerable in patients with Dementia-Related Apathy and if CVL-871 shows changes in clinical measurements of apathy.

Study identification

NCT ID
NCT04958031
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
AbbVie
Industry
Enrollment
41 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
50 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 22, 2021 (Actual)
Primary completion
Feb 12, 2025 (Actual)
Completion
Feb 12, 2025 (Actual)
Last update posted
Mar 11, 2026

2021 – 2025

United States locations

U.S. sites
17
U.S. states
12
U.S. cities
16
Facility City State ZIP Site status
Scottsdale, Arizona Scottsdale Arizona 85258 —
Little Rock, Arkansas Little Rock Arkansas 72114 —
San Diego, California San Diego California 92123 —
Santa Ana, California Santa Ana California 92705 —
New Haven, Connecticut New Haven Connecticut 06510 —
Delray Beach, Florida Delray Beach Florida 33445 —
Miami, Florida Miami Florida 33122 —
Miami, Florida Miami Florida 33180 —
Orlando, Florida Orlando Florida 32819 —
Wellington, Florida Wellington Florida 33414 —
Decatur, Georgia Decatur Georgia 30030 —
Plymouth, Massachusetts Plymouth Massachusetts 02360 —
Staten Island, New York Staten Island New York 10312 —
Columbus, Ohio Columbus Ohio 43210 —
Abington, Pennsylvania Abington Pennsylvania 19001 —
Charleston, South Carolina Charleston South Carolina 29403 —
Fairfax, Virginia Fairfax Virginia 22031 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04958031, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 11, 2026 · Synced Oct 15, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04958031 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →