A Comparison of Prolonged Exposure Therapy, Pharmacotherapy, and Their Combination for PTSD
Public ClinicalTrials.gov record NCT04961190. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Comparison of Prolonged Exposure Therapy, Pharmacotherapy, and Their Combination for PTSD: What Works Best, and for Whom
Study identification
- NCT ID
- NCT04961190
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 4
- Lead sponsor
- University of Pennsylvania
- Other
- Enrollment
- 302 participants
Conditions and interventions
Conditions
Interventions
- Pharmacotherapy with paroxetine or venlafaxine XR Drug
- Prolonged Exposure Therapy Behavioral
Drug · Behavioral
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 24, 2022
- Primary completion
- Jul 14, 2026
- Completion
- Jul 14, 2026
- Last update posted
- Jan 6, 2026
2022 – 2026
United States locations
- U.S. sites
- 7
- U.S. states
- 5
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Birmingham VA Healthcare System | Birmingham | Alabama | 35233 | — |
| VA Palo Alto Healthcare System | Menlo Park | California | 94025 | — |
| VA San Diego Healthcare System | San Diego | California | 92161 | — |
| Coatesville VA Medicial Center | Coatesville | Pennsylvania | 19320 | — |
| Corporal Michael J. Crescenz VA Medical Center | Philadelphia | Pennsylvania | 19104 | — |
| VA North Texas Healthcare System | Dallas | Texas | 75216 | — |
| Milwaukee VA Medical Center | Milwaukee | Wisconsin | 53295 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04961190, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 6, 2026 · Synced May 7, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04961190 live on ClinicalTrials.gov.