A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With Systemic Lupus Erythematosus
Public ClinicalTrials.gov record NCT04963296. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study To Evaluate The Efficacy And Safety of Obinutuzumab in Patients With Systemic Lupus Erythematosus
Study identification
- NCT ID
- NCT04963296
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Enrollment
- 303 participants
Conditions and interventions
Conditions
Interventions
- Acetaminophen/Paracetamol Drug
- Diphenhydramine hydrochloride Drug
- Methylprednisolone Drug
- Obinutuzumab Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 25, 2021
- Primary completion
- Sep 14, 2025
- Completion
- Mar 13, 2028
- Last update posted
- Apr 5, 2026
2021 – 2028
United States locations
- U.S. sites
- 14
- U.S. states
- 9
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group | Anniston | Alabama | 36207 | — |
| Unity Health - White County Medical Center- Rheumatology | Searcy | Arkansas | 72143 | — |
| Providence Medical Foundation | Fullerton | California | 92835 | — |
| Arthritis & Rheumatism | Aventura | Florida | 33180 | — |
| Great Lakes Center of Rheumatology | Lansing | Michigan | 48911 | — |
| Clinical Research Institute of Michigan, LLC | Troy | Michigan | 48047 | — |
| Northwell Health Division of Rheumatology | Great Neck | New York | 11021 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Joint & Muscle Research Institute | Charlotte | North Carolina | 28204 | — |
| The Ohio State University Wexner Medical Center | Columbus | Ohio | 43212 | — |
| Paramount Medical Research & Consulting, LLC | Middleburg Heights | Ohio | 44130 | — |
| Precision Comprehensive Clinical Research Solutions | Colleyville | Texas | 76034 | — |
| Texas Arthritis Center | El Paso | Texas | 79902 | — |
| Prolato Clinical Research Center | Houston | Texas | 77054 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 50 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04963296, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 5, 2026 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04963296 live on ClinicalTrials.gov.