ClinicalTrials.gov record
Active, not recruiting Phase 3 Interventional Results available

A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP

ClinicalTrials.gov ID: NCT04971226

Public ClinicalTrials.gov record NCT04971226. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 20, 2026, 7:28 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Multi-center, Open-label, Randomized Study of Oral Asciminib Versus Investigator Selected TKI in Patients With Newly Diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemia in Chronic Phase

Study identification

NCT ID
NCT04971226
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
405 participants

Conditions and interventions

Interventions

  • Asciminib Drug
  • Bosutinib Drug
  • Dasatinib Drug
  • Imatinib Drug
  • Nilotinib Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 100 Years
Sex
All
Healthy volunteers
Not listed

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 5, 2021
Primary completion
Nov 27, 2023
Completion
Jan 17, 2031
Last update posted
Apr 5, 2026

2021 – 2031

United States locations

U.S. sites
13
U.S. states
9
U.S. cities
12
Facility City State ZIP Site status
Rocky Mountain Cancer Centers Denver Colorado 80218
Florida Cancer Specialists Fort Myers Florida 33901
Florida Cancer Specialists Pan Tallahassee Florida 32308
University of Kentucky Lexington Kentucky 40536
Uni of Massachusetts Medical Center Worcester Massachusetts 01655
Wake Forest University Baptist Medical Center Winston-Salem North Carolina 27157
Williamette Cancer Center Eugene Oregon 97401
Oregon Health Sciences University Portland Oregon 97239
Avera Cancer Sioux Falls South Dakota 57105
Chattanooga Onc And Hem Assoc PC Chattanooga Tennessee 37404
Texas Oncology Amarillo Texas 79124
Texas Oncology-Baylor USO Dallas Texas 75246
Texas Oncology Dallas Texas 75251

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 97 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04971226, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 5, 2026 · Synced Apr 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04971226 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →