A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma
Public ClinicalTrials.gov record NCT04973605. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1b/2 Dose-Escalation and Cohort-Expansion Study to Determine the Safety and Efficacy of BGB-11417as Monotherapy, in Combination With Dexamethasone, Dexamethasone/Carfilzomib, Dexamethasone/Daratumumab, and Dexamethasone/Pomalidomide in Patients With Relapsed/Refractory Multiple Myeloma and t(11;14)
Study identification
- NCT ID
- NCT04973605
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- BeOne Medicines
- Industry
- Enrollment
- 246 participants
Conditions and interventions
Conditions
Interventions
- Carfilzomib Drug
- Daratumumab Drug
- Dexamethasone Drug
- Pomalidomide Drug
- Sonrotoclax Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 15, 2021
- Primary completion
- Oct 31, 2026
- Completion
- Oct 31, 2026
- Last update posted
- Apr 21, 2026
2021 – 2026
United States locations
- U.S. sites
- 15
- U.S. states
- 12
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama At Birmingham Hospital | Birmingham | Alabama | 35294-0004 | Recruiting |
| City of Hope National Medical Center | Duarte | California | 91010-3012 | Recruiting |
| City of Hope Irvine Lennar | Irvine | California | 92618-2377 | Recruiting |
| University of Miami | Miami | Florida | 33136-2107 | Recruiting |
| Emory University Winship Cancer Center | Atlanta | Georgia | 30322-1013 | Recruiting |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | Completed |
| Washington University School of Medicine | St Louis | Missouri | 63110-1010 | Recruiting |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601-1915 | Recruiting |
| Weill Cornell Medical College Newyork Presbyterian Hospital | New York | New York | 10065-4870 | Recruiting |
| Memorial Sloan Kettering Cancer Center Mskcc | New York | New York | 10065-6800 | Recruiting |
| The James Cancer Hospital and Solove Research Institute At Ohio State University | Columbus | Ohio | 43210-1240 | Recruiting |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112-5550 | Recruiting |
| University of Washington | Seattle | Washington | 98195 | Recruiting |
| University of Wisconsin Carbone Cancer Center | Madison | Wisconsin | 53792-0001 | Recruiting |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226-1222 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 68 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04973605, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 21, 2026 · Synced May 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04973605 live on ClinicalTrials.gov.