Phase IIa Study of ALLN-346 (Engineered Urate Oxidase) in Subjects With Hyperuricemia, Gout and Chronic Kidney Disease
Public ClinicalTrials.gov record NCT04987294. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled Study of ALLN-346 (Engineered Urate Oxidase) in Hyperuricemic Subjects With Gout and Mild to Moderate Chronic Kidney Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this Phase IIa study is to evaluate the safety, tolerability and pharmacodynamics of ALLN-346 in subjects with hyperuricemia and gout, and with mild to moderate chronic kidney disease.
Study identification
- NCT ID
- NCT04987294
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 19 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2, 2022 (Actual)
- Primary completion
- Sep 2, 2022 (Actual)
- Completion
- Sep 2, 2022 (Actual)
- Last update posted
- Jun 23, 2023
2022
United States locations
- U.S. sites
- 17
- U.S. states
- 11
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Syed Research Consultants, LLC | Muscle Shoals | Alabama | 35661 | — |
| Syed Research Consultants, LLC | Sheffield | Alabama | 35660 | — |
| Orthopedic Physicians Alaska | Anchorage | Alaska | 99508 | — |
| Allameh Medical Corporation | Mission Viejo | California | 92691 | — |
| Eastern Research, Inc. | Hialeah | Florida | 33013 | — |
| Best Quality Research, Inc. | Hialeah | Florida | 33016 | — |
| New Generation of Medical Research | Hialeah | Florida | 33016 | — |
| Kendall South Medical Center, Inc. | Miami | Florida | 33185 | — |
| The Center of Rheumatology and Bone Research | Wheaton | Maryland | 20902 | — |
| Elite Clinical Research, LLC | Jackson | Mississippi | 39202 | — |
| NY Total Medical Care, PC | Brooklyn | New York | 11215 | — |
| Burke Primary Care | Morganton | North Carolina | 28655 | — |
| Summit research Group, LLC | Stow | Ohio | 44224 | — |
| Northeast Clinical Research Center, LLC | Bethlehem | Pennsylvania | 18017 | — |
| P&I Clinical Research, LLC | Lufkin | Texas | 75904 | — |
| Briggs Clinical Research, LLC | San Antonio | Texas | 78224 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04987294, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 23, 2023 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04987294 live on ClinicalTrials.gov.