A Study of Etavopivat in Patients With Thalassemia or Sickle Cell Disease
Public ClinicalTrials.gov record NCT04987489. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Open-Label Study to Evaluate Safety and Clinical Activity of Etavopivat in Patients With Thalassemia or Sickle Cell Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This clinical trial is a Phase 2 study that will evaluate the safety and clinical activity of etavopivat in patients with thalassemia or sickle cell disease and test how well etavopivat works to lower the number of red blood cell transfusions required and increase hemoglobin.
Study identification
- NCT ID
- NCT04987489
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 53 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 28, 2022 (Actual)
- Primary completion
- Sep 3, 2025 (Actual)
- Completion
- Sep 24, 2025 (Actual)
- Last update posted
- Dec 16, 2025
2022 – 2025
United States locations
- U.S. sites
- 14
- U.S. states
- 8
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| TOI Clinical Research | Cerritos | California | 90703 | — |
| [Legal] Children's Hospital Los Angeles | Los Angeles | California | 90027 | — |
| University of Californ LA-UCLA | Los Angeles | California | 90095 | — |
| UCSF Oakland Benioff ChildHosp | Oakland | California | 94609 | — |
| [Legal] Children's Hospital of Orange County on behalf of CHOC Children's Hospital of Orange County | Orange | California | 92868 | — |
| UCI Health | Orange | California | 92868 | — |
| Children's National Health Hospital | Washington D.C. | District of Columbia | 20010 | — |
| Children's Hospital of Atlanta | Atlanta | Georgia | 30342 | — |
| [Legal] Dr. Vince Clinical Research, LLC and Dr. Vince Clinical Research, P.A. | Detroit | Michigan | 48201-2018 | — |
| Weill Medical College of Cornell University | New York | New York | 10065 | — |
| Duke University | Durham | North Carolina | 27710 | — |
| East Carolina University | Greenville | North Carolina | 27858 | — |
| [Legal] Children's Hospital Medical Center dba Cincinnati Children's | Cincinnati | Ohio | 45229 | — |
| Children's Hosptl Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 18 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04987489, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 16, 2025 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04987489 live on ClinicalTrials.gov.