ClinicalTrials.gov record
Withdrawn Phase 2 Interventional

Testing the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy Treatment During Radiation Therapy for Superior Sulcus Non-small Cell Lung Cancer

ClinicalTrials.gov ID: NCT04989283

Public ClinicalTrials.gov record NCT04989283. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 14, 2026, 11:33 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

NASSIST (Neoadjuvant Chemoradiation +/- Immunotherapy Before Surgery for Superior Sulcus Tumors): A Randomized Phase II Trial of Trimodality +/- Atezolizumab in Resectable Superior Sulcus Non-Small Cell Lung Cancer

Study identification

NCT ID
NCT04989283
Recruitment status
Withdrawn
Study type
Interventional
Phase
Phase 2
Lead sponsor
National Cancer Institute (NCI)
NIH
Enrollment
Not listed

Conditions and interventions

Interventions

  • Atezolizumab Biological
  • Biopsy Procedure
  • Biospecimen Collection Procedure
  • Carboplatin Drug
  • Cisplatin Drug
  • Computed Tomography Procedure
  • Etoposide Drug
  • External Beam Radiation Therapy Radiation
  • Magnetic Resonance Imaging Procedure
  • Paclitaxel Drug
  • Pemetrexed Drug
  • Positron Emission Tomography Procedure
  • Therapeutic Conventional Surgery Procedure

Biological · Procedure · Drug + 1 more

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 8, 2021
Primary completion
May 9, 2031
Completion
May 9, 2031
Last update posted
Sep 25, 2023

2021 – 2031

United States locations

U.S. sites
46
U.S. states
15
U.S. cities
44
Facility City State ZIP Site status
NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro Jonesboro Arkansas 72401
Moffitt Cancer Center Tampa Florida 33612
Saint Alphonsus Cancer Care Center-Boise Boise Idaho 83706
Saint Alphonsus Cancer Care Center-Caldwell Caldwell Idaho 83605
Kootenai Health - Coeur d'Alene Coeur d'Alene Idaho 83814
Saint Alphonsus Cancer Care Center-Nampa Nampa Idaho 83687
Kootenai Clinic Cancer Services - Post Falls Post Falls Idaho 83854
Kootenai Cancer Clinic Sandpoint Idaho 83864
Rush - Copley Medical Center Aurora Illinois 60504
Carle at The Riverfront Danville Illinois 61832
Carle Physician Group-Effingham Effingham Illinois 62401
Carle Physician Group-Mattoon/Charleston Mattoon Illinois 61938
Carle Cancer Center Urbana Illinois 61801
Mary Greeley Medical Center Ames Iowa 50010
McFarland Clinic - Ames Ames Iowa 50010
McFarland Clinic - Boone Boone Iowa 50036
McFarland Clinic - Trinity Cancer Center Fort Dodge Iowa 50501
McFarland Clinic - Jefferson Jefferson Iowa 50129
McFarland Clinic - Marshalltown Marshalltown Iowa 50158
Baptist Memorial Hospital and Cancer Center-Golden Triangle Columbus Mississippi 39705
Baptist Cancer Center-Grenada Grenada Mississippi 38901
Baptist Memorial Hospital and Cancer Center-Union County New Albany Mississippi 38652
Baptist Memorial Hospital and Cancer Center-Oxford Oxford Mississippi 38655
Baptist Memorial Hospital and Cancer Center-Desoto Southhaven Mississippi 38671
Billings Clinic Cancer Center Billings Montana 59101
Bozeman Deaconess Hospital Bozeman Montana 59715
Benefis Healthcare- Sletten Cancer Institute Great Falls Montana 59405
Kalispell Regional Medical Center Kalispell Montana 59901
Community Medical Hospital Missoula Montana 59804
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center Lebanon New Hampshire 03756
Mount Sinai Chelsea New York New York 10011
Mount Sinai Hospital New York New York 10029
Adena Regional Medical Center Chillicothe Ohio 45601
University of Cincinnati Cancer Center-UC Medical Center Cincinnati Ohio 45219
The Mark H Zangmeister Center Columbus Ohio 43219
University of Cincinnati Cancer Center-West Chester West Chester Ohio 45069
Saint Ann's Hospital Westerville Ohio 43081
Genesis Healthcare System Cancer Care Center Zanesville Ohio 43701
Cancer Centers of Southwest Oklahoma Research Lawton Oklahoma 73505
University of Oklahoma Health Sciences Center Oklahoma City Oklahoma 73104
Saint Alphonsus Medical Center-Ontario Ontario Oregon 97914
Baptist Memorial Hospital and Cancer Center-Collierville Collierville Tennessee 38017
Baptist Memorial Hospital and Cancer Center-Memphis Memphis Tennessee 38120
Norris Cotton Cancer Center-North Saint Johnsbury Vermont 05819
Gundersen Lutheran Medical Center La Crosse Wisconsin 54601
Marshfield Clinic-Minocqua Center Minocqua Wisconsin 54548

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04989283, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 25, 2023 · Synced May 14, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04989283 live on ClinicalTrials.gov.

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