A Study of SEA-CD40 Given With Other Drugs in Cancers
Public ClinicalTrials.gov record NCT04993677. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-label, Phase 2 Basket Study of SEA-CD40 Combination Therapies in Advanced Malignancies
Study identification
- NCT ID
- NCT04993677
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Seagen Inc.
- Industry
- Enrollment
- 77 participants
Conditions and interventions
Conditions
Interventions
- SEA-CD40 Drug
- carboplatin Drug
- pembrolizumab (KEYTRUDA®) Drug
- pemetrexed Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 5, 2021
- Primary completion
- Jan 2, 2024
- Completion
- Nov 24, 2024
- Last update posted
- May 10, 2025
2021 – 2024
United States locations
- U.S. sites
- 23
- U.S. states
- 16
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Highlands Oncology Group | Springdale | Arkansas | 72762 | — |
| The Angeles Clinic and Research Institute | Los Angeles | California | 90025 | — |
| California Pacific Medical Center Research Institute/Sutter Medical Centre | San Francisco | California | 94115 | — |
| University of California at San Francisco | San Francisco | California | 94134 | — |
| Florida Cancer Specialists - South Region | Fort Myers | Florida | 33901 | — |
| Florida Cancer Specialists - North Region | St. Petersburg | Florida | 33705 | — |
| University Cancer & Blood Center, LLC | Athens | Georgia | 30607 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Community Health Network | Indianapolis | Indiana | 46250 | — |
| American Oncology Networks LLC | Baton Rouge | Louisiana | 70809 | — |
| Allina Health Cancer Institute | Minneapolis | Minnesota | 55407 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Regions Cancer Care Center | Saint Paul | Minnesota | 55101 | — |
| Morristown Medical Center/ Carol G. Simon Cancer Center | Morristown | New Jersey | 07960 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Gabrail Cancer Center Research, LLC | Canton | Ohio | 44718 | — |
| Cleveland Clinic - Taussig Cancer Institute | Cleveland | Ohio | 44195 | — |
| Kaiser Permanente Oregon | Portland | Oregon | 97227 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Tennessee Oncology-Nashville/Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | — |
| University of Texas Southwestern/Simmons Cancer Center | Dallas | Texas | 75390 | — |
| MD Anderson Cancer Center / University of Texas | Houston | Texas | 77030-4095 | — |
| Carbone Cancer Center / University of Wisconsin | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04993677, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 10, 2025 · Synced May 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04993677 live on ClinicalTrials.gov.