TEPEZZA® (Teprotumumab-trbw) Post-Marketing Requirement Study
Public ClinicalTrials.gov record NCT05002998. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3b/4, Double-masked, Randomized, International, Parallel-assignment, Multicenter Trial in Patients With Thyroid Eye Disease to Evaluate the Safety and Tolerability of Different Dosing Durations of Teprotumumab
Study identification
- NCT ID
- NCT05002998
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Lead sponsor
- Amgen
- Industry
- Enrollment
- 313 participants
Conditions and interventions
Conditions
Interventions
- Placebo Drug
- Teprotumumab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 15, 2021
- Primary completion
- Dec 18, 2025
- Completion
- Dec 18, 2025
- Last update posted
- Jan 14, 2026
2021 – 2025
United States locations
- U.S. sites
- 7
- U.S. states
- 5
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Private Practice of Raymond Douglas, MD - Beverly Hills | Beverly Hills | California | 90210-5192 | — |
| USC Roski Eye Institute - Los Angeles | Los Angeles | California | 90033 | — |
| Stanford University | Palo Alto | California | 94303-3216 | — |
| University of Colorado - Eye Center - PPDS | Aurora | Colorado | 80045-2517 | — |
| Bascom Palmer Eye Institute | Miami | Florida | 33136-1119 | — |
| Mayo Clinic - PPDS | Rochester | Minnesota | 55905-0001 | — |
| Casey Eye Institute - OHSU | Portland | Oregon | 97239-3130 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 21 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05002998, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 14, 2026 · Synced May 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05002998 live on ClinicalTrials.gov.