Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan
Public ClinicalTrials.gov record NCT05005403. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Global First-in-Human Study in NSCLC, HNSCC, and Solid Tumors With Azirkitug as a Single Agent and in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan
Study identification
- NCT ID
- NCT05005403
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- AbbVie
- Industry
- Enrollment
- 694 participants
Conditions and interventions
Conditions
Interventions
- Azirkitug Drug
- Bevacizumab Drug
- Budigalimab Drug
- Telisotuzumab Adizutecan Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 31, 2021
- Primary completion
- Jun 30, 2027
- Completion
- Jun 30, 2027
- Last update posted
- Apr 12, 2026
2021 – 2027
United States locations
- U.S. sites
- 18
- U.S. states
- 11
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| City of Hope National Medical Center /ID# 276272 | Duarte | California | 91010 | Recruiting |
| City of Hope - Orange County Lennar Foundation Cancer Center /ID# 278589 | Irvine | California | 92618 | Recruiting |
| University of Illinois Hospital and Health Sciences System /ID# 251750 | Chicago | Illinois | 60607 | Recruiting |
| Fort Wayne Medical Oncology and Hematology, Inc /ID# 232593 | Fort Wayne | Indiana | 46804 | Recruiting |
| Community Health Network, Inc. /ID# 243011 | Indianapolis | Indiana | 46250-2042 | Recruiting |
| Norton Cancer Institute /ID# 248903 | Louisville | Kentucky | 40241-2832 | Recruiting |
| START Midwest /ID# 248685 | Grand Rapids | Michigan | 49546-7062 | Recruiting |
| M Health Fairview University of Minnesota Medical Center - East Bank /ID# 276200 | Minneapolis | Minnesota | 55455 | Recruiting |
| Nebraska Cancer Specialists - Omaha - Wright Street /ID# 247399 | Omaha | Nebraska | 68130 | Recruiting |
| Duke Cancer Institute /ID# 276267 | Durham | North Carolina | 27710 | Recruiting |
| Carolina BioOncology Institute /ID# 232597 | Huntersville | North Carolina | 28078 | Recruiting |
| NEXT Oncology Austin /ID# 243005 | Austin | Texas | 78705-1171 | Recruiting |
| The University of Texas MD Anderson Cancer Center /ID# 270059 | Houston | Texas | 77030 | Recruiting |
| Next Oncology - Irving /ID# 276254 | Irving | Texas | 75039 | Recruiting |
| NEXT Oncology /ID# 243007 | San Antonio | Texas | 78229 | Recruiting |
| South Texas Accelerated Research Therapeutics (START) /ID# 276268 | San Antonio | Texas | 78229 | Recruiting |
| Start Mountain Region /ID# 276270 | West Valley City | Utah | 84119 | Recruiting |
| Virginia Cancer Specialists - Fairfax /ID# 232592 | Fairfax | Virginia | 22031 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 26 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05005403, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 12, 2026 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05005403 live on ClinicalTrials.gov.