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ClinicalTrials.gov record
Terminated Phase 2Phase 3 Interventional Results available

Evaluation of Protease Inhibition for COVID-19 in Standard-Risk Patients (EPIC-SR).

ClinicalTrials.gov ID: NCT05011513

Public ClinicalTrials.gov record NCT05011513. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 10:17 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

AN INTERVENTIONAL EFFICACY AND SAFETY, PHASE 2/3, DOUBLE-BLIND, 2 ARM STUDY TO INVESTIGATE ORALLY ADMINISTERED PF 07321332/RITONAVIR COMPARED WITH PLACEBO IN NONHOSPITALIZED SYMPTOMATIC ADULT PARTICIPANTS WITH COVID-19 WHO ARE AT LOW RISK OF PROGRESSING TO SEVERE ILLNESS

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary hypothesis to be tested is whether or not there is a difference in time to sustained alleviation of all targeted COVID-19 signs and symptoms through Day 28 between PF-07321332/ritonavir and placebo.

Study identification

NCT ID
NCT05011513
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
Pfizer
Industry
Enrollment
1,440 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 25, 2021 (Actual)
Primary completion
Jul 25, 2022 (Actual)
Completion
Jul 25, 2022 (Actual)
Last update posted
Aug 14, 2023

2021 – 2022

United States locations

U.S. sites
78
U.S. states
15
U.S. cities
54
Facility City State ZIP Site status
Cahaba Research Inc Pelham Alabama 35124 —
The Institute for Liver Health dba Arizona Clinical Trials Mesa Arizona 85210 —
Matrix Mobile Health Clinic #49, #35, and #62 Scottsdale Arizona 85258 —
The Institute for Liver Health dba Arizona Clinical Trials Tucson Arizona 85712 —
Hope Clinical Research Canoga Park California 91303 —
Lightship El Segundo California 90245 —
Ascada Research Fullerton California 92835 —
Atella Clinical Research LLC. La Palma California 90623 —
Ark Clinical Research Long Beach California 90806 —
South Bay Clinical Research Institute Redondo Beach California 90277 —
Benchmark Research Sacramento California 95864 —
Optimus Medical Group San Francisco California 94102 —
Hope Clinical Research (COVID Satellite Site) West Hills California 91304 —
Future Innovative Treatments, LLC Colorado Springs Colorado 80907 —
Synergy Healthcare Bradenton Florida 34208 —
MOORE Clinical Research, Inc. Brandon Florida 33511 —
TrueBlue Clinical Research Brandon Florida 33511 —
Herco Medical and Research Center Inc Coral Gables Florida 33134 —
Advance Clinical Research Group Cutler Bay Florida 33157 —
Beautiful Minds Clinical Research Center Cutler Bay Florida 33157 —
Omega Research Orlando, LLC DeBary Florida 32713 —
Eastern Research Inc Hialeah Florida 33013 —
Inpatient Research Clinic Hialeah Florida 33013 —
Doral Medical Research, LLC Hialeah Florida 33016 —
Unlimited Medical Research Group, LLC Hialeah Gardens Florida 33018 —
ASCLEPES Research Centers Lutz Florida 33549 —
Angels Clinical Research Institute Miami Florida 33122 —
LCC Medical Research Institute, LLC Miami Florida 33126 —
Premium Medical Research Corp Miami Florida 33126 —
Global Health Clinical Trials Corp Miami Florida 33135 —
South Florida Research Center, Inc. Miami Florida 33135 —
I.V.A.M. Clinical & Investigational Center, LLC Miami Florida 33144 —
C'A Research Miami Florida 33174 —
ProLive Medical Research, Corp. Miami Florida 33175 —
Entrust Clinical Research Miami Florida 33176 —
Reed Medical Research Miami Florida 33176 —
Kendall South Medical Center, Inc. Miami Florida 33185 —
Clinical Site Partners, Inc d/b/a CSP Miami Miami Florida 33186 —
Coral Research Clinic Corp Miami Florida 33186 —
Pro-Care Research Center, Corp. Miami Gardens Florida 33014 —
Savin Medical Group, LLC Miami Lakes Florida 33014 —
Omega Research Orlando, LLC Orlando Florida 32808 —
CDC Research Institute Port Saint Lucie Florida 34952 —
USPA Advance Concept Medical Research Group LLC South Miami Florida 33143 —
ASCLEPES Research Centers Spring Hill Florida 34609 —
GCP, Global Clinical Professionals St. Petersburg Florida 33705 —
Sunrise Research Institute Sunrise Florida 33325 —
Santos Research Center, CORP Tampa Florida 33615 —
Clinical Site Partners, Inc. dba CSP Orlando Winter Park Florida 32789 —
Accellacare Ames Iowa 50010 —
McFarland Clinic, PC Ames Iowa 50010 —
New Orleans Sinus Center (COVID-19 Testing) Marrero Louisiana 70072 —
Tandem Clinical Research GI, LLC Marrero Louisiana 70072 —
Southern Clinical Research Associates, LLC Metairie Louisiana 70001 —
Mercury Street Medical Group, PLLC Butte Montana 59701 —
Excel Clinical research Las Vegas Nevada 89109 —
AXCES Research Group Santa Fe New Mexico 87505 —
NYC Health + Hospitals / Harlem New York New York 10037 —
Monroe Biomedical Research Monroe North Carolina 28112 —
Accellacare Wilmington North Carolina 28401 —
Innovo Research: Wilmington Health Wilmington North Carolina 28401 —
Avera McKennan Hospital & University Health Center Sioux Falls South Dakota 57105 —
Avera Research Institute Sioux Falls South Dakota 57108 —
PharmaTex Research, LLC Amarillo Texas 79109 —
ARC Clinical Research at William Cannon Austin Texas 78745 —
St Hope Foundation Bellaire Texas 77401 —
Conroe Willis Medical Research Conroe Texas 77304 —
South Texas Clinical Research Corpus Christi Texas 78413 —
SignatureCare Emergency Center Houston Texas 77008 —
Trio Clinical Trials, LLC Houston Texas 77008 —
Next Level Urgent Care Houston Texas 77057 —
LinQ Research, LLC Pearland Texas 77584 —
Epic Medical Research Red Oak Texas 75154 —
Endeavor Clinical Trials, LLC San Antonio Texas 78229 —
BFHC Research San Antonio Texas 78249 —
Tranquility Research Webster Texas 77598 —
TMPG Clinical Research Newport News Virginia 23606 —
TPMG Clinical Research Newport News Virginia 23606 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 147 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05011513, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 14, 2023 · Synced Oct 19, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05011513 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →