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Completed Phase 1 Interventional

Study of Oral LOXO-338 in Patients With Advanced Blood Cancers

ClinicalTrials.gov ID: NCT05024045

Public ClinicalTrials.gov record NCT05024045. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 5, 2026, 8:49 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 Study of Oral LOXO-338, a Selective BCL-2 Inhibitor, in Patients With Advanced Hematologic Malignancies

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to find out whether the study drug, LOXO-338, is safe and effective in patients with advanced blood cancer. Patients must have already received standard therapy. The study may last up to approximately 3 years.

Study identification

NCT ID
NCT05024045
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Eli Lilly and Company
Industry
Enrollment
27 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 30, 2021 (Actual)
Primary completion
Jun 14, 2023 (Actual)
Completion
Mar 2, 2026 (Actual)
Last update posted
Oct 6, 2026

2021 – 2026

United States locations

U.S. sites
13
U.S. states
11
U.S. cities
13
Facility City State ZIP Site status
The University of Arizona Cancer Center Tucson Arizona 85724 —
City of Hope National Medical Center Duarte California 91010-0269 —
University of California San Francisco, Medical Center at Paranassus San Francisco California 94117 —
Mayo Clinic in Florida Jacksonville Florida 32224 —
Sylvester Comprehensive Cancer Center Miami Florida 33136 —
Emory University Atlanta Georgia 30322 —
Indiana Blood & Marrow Transplantation (IBMT) Indianapolis Indiana 46237 —
University of Kansas Medical Center Westwood Kansas 66205 —
Tufts Medical Center Boston Massachusetts 02111 —
Mayo Clinic Rochester Minnesota 55905-0002 —
Memorial Sloan Kettering Cancer Center New York New York 10065 —
Swedish Medical Center Seattle Washington 98104 —
Medical College of Wisconsin Milwaukee Wisconsin 53226 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05024045, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 6, 2026 · Synced Nov 5, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05024045 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →