ClinicalTrials.gov record
Global Study of MK-2060 (Anti-Factor XI Monoclonal Antibody) in Participants With End Stage Renal Disease Receiving Hemodialysis (FXI Hemodialysis Study) (MK-2060-007)
ClinicalTrials.gov ID: NCT05027074
Public ClinicalTrials.gov record NCT05027074. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Parallel-group, Placebo-controlled, Double-blind, Event-driven, Multi-center Phase 2 Clinical Outcome Trial of Prevention of Arteriovenous Graft Thrombosis and Safety of MK-2060 in Patients With End Stage Renal Disease Receiving Hemodialysis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy and safety of two different doses of MK-2060 (a monoclonal antibody against Factor XI) in end stage renal disease (ESRD) participants receiving hemodialysis via an arteriovenous graft (AVG). Data from this study will be used to aid dose selection of MK-2060 in future studies. The primary hypothesis is that at least one of the MK-2060 doses is superior to placebo in increasing the time to first occurrence of AVG event.
Study identification
- NCT ID
- NCT05027074
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 506 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 17, 2021 (Actual)
- Primary completion
- Oct 30, 2024 (Actual)
- Completion
- Feb 13, 2025 (Actual)
- Last update posted
- Feb 11, 2026
2021 – 2025
United States locations
- U.S. sites
- 77
- U.S. states
- 25
- U.S. cities
- 62
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Nephrology Consultants ( Site 0681) | Huntsville | Alabama | 35805 | — |
| AKDHC MEDICAL RESEARCH SERVICES, LLC-Maryvale ( Site 0723) | Phoenix | Arizona | 85035 | — |
| AKDHC Medical Research Services, LLC ( Site 0629) | Tucson | Arizona | 85741 | — |
| DaVita Anaheim West Dialysis-Davita Anaheim West Dialysis - Ismail ( Site 0562) | Anaheim | California | 92801 | — |
| DaVita Bakersfield Oak Street Dialysis-Clinical Research ( Site 0547) | Bakersfield | California | 93304 | — |
| Fresenius Kidney Care Bakersfield Northeast ( Site 0647) | Bakersfield | California | 93306 | — |
| Fresenius Kidney Care Meadows Field ( Site 0618) | Bakersfield | California | 93308 | — |
| California Institute Of Renal Research ( Site 0660) | Chula Vista | California | 91910 | — |
| Citrus Dialysis Center ( Site 0609) | Covina | California | 91723 | — |
| California Institute Of Renal Research ( Site 0679) | El Centro | California | 92243 | — |
| California Institute of Renal Research ( Site 0566) | Escondido | California | 92025 | — |
| Fresenius Kidney Care Newhope Fountain Valley ( Site 0617) | Fountain Valley | California | 92708 | — |
| DaVita Glendale Heights ( Site 0604) | Glendale | California | 91201 | — |
| DaVita West Glendale Dialysis ( Site 0579) | Glendale | California | 91205 | — |
| DaVita North Glendale ( Site 0552) | Glendale | California | 91206 | — |
| California Institute of Renal Research - La Mesa ( Site 0682) | La Mesa | California | 91941 | — |
| La Puente Dialysis Center ( Site 0610) | La Puente | California | 91744 | — |
| Academic Medical Research Institute ( Site 0533) | Los Angeles | California | 90022 | — |
| DaVita Kidney Center - East LA Plaza Dialysis ( Site 0548) | Los Angeles | California | 90033 | — |
| DaVita Crescent Heights Dialysis Center ( Site 0574) | Los Angeles | California | 90048 | — |
| North America Research Institute ( Site 0587) | Lynwood | California | 90262 | — |
| North America Research Institute ( Site 0612) | Lynwood | California | 90262 | — |
| Valley Renal Medical Group Research-Clinical Research ( Site 0651) | Northridge | California | 91343 | — |
| California Institute of Renal Research - Kearny Mesa ( Site 0678) | San Diego | California | 92111 | — |
| North America Research Institute ( Site 0611) | San Dimas | California | 91773 | — |
| DaVita Van Nuys Dialysis ( Site 0538) | Van Nuys | California | 91405 | — |
| Desert Cities Diaylsis-Clinical Research ( Site 0615) | Victorville | California | 92392 | — |
| DaVita Clinical Research - Hartford ( Site 0507) | Hartford | Connecticut | 06112 | — |
| DaVita Clinical Research - Middlebury ( Site 0511) | Middlebury | Connecticut | 06762 | — |
| Research Physicians Network Alliance ( Site 0563) | Boca Raton | Florida | 33431 | — |
| Horizon Research Group ( Site 0578) | Coral Gables | Florida | 33134 | — |
| Horizon Research Group ( Site 0581) | Coral Gables | Florida | 33134 | — |
| Elixia at Florida Kidney Physicians - Southeast ( Site 0602) | Fort Lauderdale | Florida | 33308 | — |
| South Florida Research Institute ( Site 0656) | Fort Lauderdale | Florida | 33313 | — |
| Elixia Clinical Research Collaborative (CRC) - Southeast Florida ( Site 0728) | Hollywood | Florida | 33020 | — |
| Pines Clinical Research ( Site 0605) | Hollywood | Florida | 33024 | — |
| Floridian Clinical Research, LLC ( Site 0684) | Miami Lakes | Florida | 33016 | — |
| Omega Research Orlando ( Site 0645) | Orlando | Florida | 32808 | — |
| Genesis Clinical Research, LLC ( Site 0585) | Tampa | Florida | 33603 | — |
| Genesis Clinical Research, LLC ( Site 0594) | Tampa | Florida | 33603 | — |
| Genesis Clinical Research, LLC ( Site 0680) | Tampa | Florida | 33603 | — |
| DaVita Clinical Research - Columbus ( Site 0532) | Columbus | Georgia | 31904 | — |
| Renal Physicians of Georgia ( Site 0577) | Macon | Georgia | 31217 | — |
| DaVita East Georgia Dialysis Unit ( Site 0536) | Statesboro | Georgia | 30458 | — |
| University of Chicago Medical Center-Medicine - Section of Nephrology ( Site 0595) | Chicago | Illinois | 60637 | — |
| Nephrology Specialists - Merrillville ( Site 0537) | Merrillville | Indiana | 46410 | — |
| Nephrology Specialists - Michigan City ( Site 0541) | Michigan City | Indiana | 46360 | — |
| Capital Nephrology ( Site 0596) | Greenbelt | Maryland | 20770 | — |
| Henry Ford Hospital-Nephrology and Hypertension ( Site 0694) | Detroit | Michigan | 48202 | — |
| St. Clair Nephrology Research - Roseville ( Site 0597) | Roseville | Michigan | 48066 | — |
| DaVita Clinical Research ( Site 0502) | Minneapolis | Minnesota | 55404 | — |
| Fresenius Kidney Care Brookhaven ( Site 0693) | Brookhaven | Mississippi | 39601 | — |
| Clinical Research Consultants, LLC ( Site 0542) | Kansas City | Missouri | 64111 | — |
| Somnos Clinical Research ( Site 0669) | Lincoln | Nebraska | 68505 | — |
| DaVita Five Star Dialysis Center ( Site 0509) | Las Vegas | Nevada | 89128 | — |
| Renal Medicine Associates ( Site 0690) | Albuquerque | New Mexico | 87109 | — |
| Capital District Renal Physicians ( Site 0633) | Albany | New York | 12209 | — |
| Ridgewood Dialysis Center ( Site 0725) | Ridgewood | New York | 11385 | — |
| Albert Einstein College of Medicine-Department of Medicine-Nephrology Einstein ( Site 0628) | The Bronx | New York | 10461 | — |
| DaVita Clinical Researh ( Site 0501) | The Bronx | New York | 10461 | — |
| Fresenius Kidney Care - Charlotte ( Site 0686) | Charlotte | North Carolina | 28208 | — |
| Durham Nephrology Associates ( Site 0655) | Durham | North Carolina | 27704 | — |
| East Carolina University-Department of Nephrology & Hypertension ( Site 0663) | Greenville | North Carolina | 27834 | — |
| Kidney and Hypertension Center ( Site 0571) | Roseburg | Oregon | 97471 | — |
| Northeast Clinical Research Center ( Site 0653) | Bethlehem | Pennsylvania | 18017 | — |
| Elixia at Clinical Renal Associates ( Site 0677) | Upland | Pennsylvania | 19013 | — |
| South Carolina Nephrology & Hypertension Center-Research ( Site 0672) | Orangeburg | South Carolina | 29118 | — |
| Knoxville Kidney Center ( Site 0689) | Knoxville | Tennessee | 37923 | — |
| Renal Disease Research Institute ( Site 0621) | Dallas | Texas | 75235 | — |
| DaVita Clinical Research - El Paso ( Site 0505) | El Paso | Texas | 79925 | — |
| DaVita Clinical Research - Houston ( Site 0508) | Houston | Texas | 77004 | — |
| Clinical Research Strategies ( Site 0625) | Houston | Texas | 77090 | — |
| Southwest Houston Research ( Site 0649) | Houston | Texas | 77099 | — |
| Texas Institute for Kidney and Endocrine Disorders ( Site 0626) | Lufkin | Texas | 75904 | — |
| Gamma Medical Research ( Site 0688) | McAllen | Texas | 78503 | — |
| DaVita Clinical Research - Norfolk ( Site 0513) | Norfolk | Virginia | 23502 | — |
| DaVita Clinical Research - Milwaukee ( Site 0512) | Wauwatosa | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 43 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05027074, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 11, 2026 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05027074 live on ClinicalTrials.gov.