Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal Metastases
Public ClinicalTrials.gov record NCT05034497. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter Phase 1 Clinical Study to Determine the Maximum Tolerated Dose/Maximum Feasible Dose, Safety,& Efficacy of Single Dose Rhenium-186 NanoLiposome (186RNL) Administered Via Intraventricular Catheter for Leptomeningeal Metastases
Study identification
- NCT ID
- NCT05034497
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Plus Therapeutics
- Industry
- Enrollment
- 18 participants
Conditions and interventions
Conditions
Interventions
- 186RNL Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 5, 2021
- Primary completion
- Dec 20, 2025
- Completion
- Jun 29, 2026
- Last update posted
- Mar 25, 2025
2021 – 2026
United States locations
- U.S. sites
- 6
- U.S. states
- 4
- U.S. cities
- 6
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Northwestern Memorial Hospital Olson Pavilion | Chicago | Illinois | 60611 | — |
| Northshore University Hospital | Manhasset | New York | 11030 | — |
| Lenox Hill Hospital | New York | New York | 10075 | — |
| Ohio State University Hospital | Columbus | Ohio | 43201 | — |
| Universiy of Texas Southwestern Medical Center | Dallas | Texas | 75390 | — |
| UT Health Science Center San Antonio / Mays Cancer Center | San Antonio | Texas | 78229 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05034497, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 25, 2025 · Synced May 16, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05034497 live on ClinicalTrials.gov.