Bridge to HOPE: Hypothermic Oxygenated Perfusion Versus Cold Storage Prior to Liver Transplantation
Public ClinicalTrials.gov record NCT05045794. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Multicenter, Prospective, Open-label, Randomized Controlled Clinical Trial to Compare the Safety & Effectiveness of the VitaSmart Liver Machine Perfusion System With Static Cold Storage for Organ Preservation Prior to Liver Transplantation
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a prospective, multi-center, controlled, randomized, pivotal study to evaluate the safety and effectiveness of the VitaSmart™ Liver Machine Perfusion System by comparing clinical outcomes in patients undergoing liver transplantation with ex-vivo liver preservation using static cold storage (SCS) followed by hypothermic oxygenated machine perfusion (HOPE) versus SCS only.
Study identification
- NCT ID
- NCT05045794
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 228 participants
Conditions and interventions
Conditions
Interventions
Device · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 16, 2021 (Actual)
- Primary completion
- May 19, 2023 (Actual)
- Completion
- May 31, 2024 (Actual)
- Last update posted
- Jul 22, 2026
2021 – 2024
United States locations
- U.S. sites
- 15
- U.S. states
- 12
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Loma Linda University Medical Center | San Bernadino | California | 92408 | — |
| University of California San Francisco | San Francisco | California | 94143 | — |
| Stanford University Medical Center | Stanford | California | 94305 | — |
| Mayo Clinic | Jacksonville | Florida | 32224 | — |
| Cleveland Clinic | Weston | Florida | 33331 | — |
| Indiana University | Indianapolis | Indiana | 46202 | — |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| Lahey Hospital and Medical Center | Burlington | Massachusetts | 01895 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Washington University St. Louis | St Louis | Missouri | 63110 | — |
| Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Mount Sinai Hospital | New York | New York | 10029 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| University of Wisconsin Madison | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05045794, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 22, 2026 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05045794 live on ClinicalTrials.gov.