ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Public ClinicalTrials.gov record NCT05059444. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Study identification
- NCT ID
- NCT05059444
- Recruitment status
- Recruiting
- Study type
- Observational
- Phase
- Not listed
- Lead sponsor
- Guardant Health, Inc.
- Industry
- Enrollment
- 2,020 participants
Conditions and interventions
Conditions
- Bladder Carcinoma
- Cutaneous Melanoma
- Endometrial Carcinoma
- Epithelial Ovarian Carcinoma
- Esophageal Carcinoma
- Fallopian Tube Carcinoma
- Gastric Adenocarcinoma
- Gastroesophageal Junction Carcinoma
- Invasive Breast Carcinoma
- Non-small Cell Lung Cancer
- Pancreatic Adenocarcinoma
- Rectal Adenocarcinoma
- Renal Cell Carcinoma
- Renal Pelvis Carcinoma
- Squamous Cell Carcinoma of the Head and Neck
- Ureter Carcinoma
Interventions
- Guardant Reveal Diagnostic Test
Diagnostic Test
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 6, 2021
- Primary completion
- Jul 31, 2029
- Completion
- Jul 31, 2029
- Last update posted
- Aug 21, 2025
2021 – 2029
United States locations
- U.S. sites
- 33
- U.S. states
- 20
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35205 | Recruiting |
| Ironwood Cancer & Research Centers | Chandler | Arizona | 85224 | Recruiting |
| Genesis Cancer Center | Hot Springs | Arkansas | 71913 | Terminated |
| University of California, San Diego | La Jolla | California | 92093 | Recruiting |
| Hoag Memorial Hospital Presbyterian | Newport Beach | California | 92663 | Recruiting |
| Redwood City | Redwood City | California | 94063 | Recruiting |
| Sutter Institute for Medical Research | Sacramento | California | 95816 | Terminated |
| University of Colorado | Aurora | Colorado | 80045 | Recruiting |
| Memorial Healthcare System | Hollywood | Florida | 33021 | Recruiting |
| The Oncology Institute of Hope & Innovation | Lakeland | Florida | 33812 | Recruiting |
| Tulane Cancer Center | New Orleans | Louisiana | 70112 | Recruiting |
| Christus Highland/ Boniol | Shreveport | Louisiana | 71105 | Recruiting |
| Central Maine Medical Center | Lewiston | Maine | 04240 | Recruiting |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | Terminated |
| Cancer & Hematology Centers of Western Michigan | Grand Rapids | Michigan | 49503 | Recruiting |
| Mayo Clinic (Rochester) | Rochester | Minnesota | 55905 | Recruiting |
| Astera Cancer Care | East Brunswick | New Jersey | 08816 | Recruiting |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | Terminated |
| UNC- Chapel Hill | Chapel Hill | North Carolina | 27599 | Recruiting |
| The Christ Hospital Cancer Center | Cincinnati | Ohio | 45219 | Terminated |
| Cleveland Clinic | Cleveland | Ohio | 44195 | Recruiting |
| Toledo Clinic Cancer Center | Toledo | Ohio | 43623 | Recruiting |
| Crozer-Keystone Health System | Broomall | Pennsylvania | 19008 | Terminated |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | Recruiting |
| Cancer Care Associates of York | York | Pennsylvania | 17403 | Recruiting |
| Carolina Urologic Research Center | Myrtle Beach | South Carolina | 29572 | Recruiting |
| Carolina Blood and Cancer Care Associates | Rock Hill | South Carolina | 29732 | Recruiting |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | Recruiting |
| DHR Health Advance Care Center | Edinburg | Texas | 78539 | Recruiting |
| The Center for Cancer and Blood Disorders | Forth Worth | Texas | 76104 | Recruiting |
| The University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | Recruiting |
| Utah Cancer Specialists | Salt Lake City | Utah | 84106 | Recruiting |
| ThedaCare Regional Cancer Center | Appleton | Wisconsin | 54911 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 24 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05059444, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 21, 2025 · Synced Apr 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05059444 live on ClinicalTrials.gov.