An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut Syndrome

ClinicalTrials.gov ID: NCT05066217

Public ClinicalTrials.gov record NCT05066217. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 7, 2026, 1:18 PM EDT

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Official title

Multicenter, Randomized, Double-blind, Placebo-controlled Trial of Clemizole HCl as Adjunctive Therapy in Patients With Lennox-Gastaut Syndrome

Study identification

NCT ID: NCT05066217
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: Epygenix; Industry
Enrollment: 260 participants

Conditions and interventions

Conditions

Lennox Gastaut Syndrome

Interventions

Clemizole HCl Drug
Placebo Drug

Drug

Eligibility (public fields only)

Age range: 2 Years to 55 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Apr 8, 2025
Primary completion: Oct 31, 2026
Completion: Oct 31, 2029
Last update posted: Apr 14, 2026

2025 – 2029

United States locations

U.S. sites: 20
U.S. states: 13
U.S. cities: 17

Facility	City	State	ZIP	Site status
Arkansas Children's Hospital	Little Rock	Arkansas	72202	Active, not recruiting
UC Irvine Medical Center	Orange	California	92868	Active, not recruiting
UCI Center for Innovative Health Therapies	Orange	California	92868	Recruiting
Nemours Children's Health	Wilmington	Delaware	19803	Not yet recruiting
Rare Disease Research	Kissimmee	Florida	34746	Suspended
University of Miami Miller School of Medicine	Miami	Florida	33136	Recruiting
Pediatric Neurology and Epilepsy Specialists	Winter Park	Florida	32789	Active, not recruiting
Re:Cognition Health	Chicago	Illinois	60611	Recruiting
Norton Children's Medical Center	Louisville	Kentucky	40202	Active, not recruiting
Henry Ford Hospital	Detroit	Michigan	48202	Active, not recruiting
Minnesota Epilepsy Group, P.A.	Roseville	Minnesota	55102	Active, not recruiting
Children's Nebraska	Omaha	Nebraska	68114	Active, not recruiting
Neurology Center for Epilepsy and Seizures	Marlboro	New Jersey	07746	Recruiting
Tekton Research	Marlboro	New Jersey	07746	Recruiting
Weill Cornell Medicine/New York Presbyterian Hospital	New York	New York	10021	Recruiting
Atrium Health STRIVE Research	Charlotte	North Carolina	28207	Active, not recruiting
On-Site Clinical Solution	Charlotte	North Carolina	28211	Active, not recruiting
Duke University Medical Center	Durham	North Carolina	27705	Recruiting
PPD Virtual-Science 37, Inc.	Morrisville	North Carolina	27560	Active, not recruiting
UTHealth Houston	Houston	Texas	77030	Active, not recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05066217, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 14, 2026 · Synced May 7, 2026

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The complete protocol, eligibility criteria, and contact information for NCT05066217 live on ClinicalTrials.gov.

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