ClinicalTrials.gov record
Study to Assess Rifaximin Soluble Solid Dispersion (SSD) for the Delay of Encephalopathy Decompensation in Cirrhosis
ClinicalTrials.gov ID: NCT05071716
Public ClinicalTrials.gov record NCT05071716. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Assess the Efficacy and Safety of Rifaximin Soluble Solid Dispersion (SSD) for the Delay of Encephalopathy Decompensation in Cirrhosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Study RNLC3131 is a Phase 3, randomized, double-blind, placebo-controlled, multicenter study to assess the efficacy and safety of rifaximin SSD-40mg IR for the delay of the first episode of overt hepatic encephalopathy (OHE) decompensation in liver cirrhosis, defined by the presence of medically controlled ascites.
Study identification
- NCT ID
- NCT05071716
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 524 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 7, 2022 (Actual)
- Primary completion
- Sep 2025 (Estimated)
- Completion
- Sep 2025 (Estimated)
- Last update posted
- Jul 24, 2025
2022 – 2025
United States locations
- U.S. sites
- 139
- U.S. states
- 34
- U.S. cities
- 106
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Bausch Site 182 | Dothan | Alabama | 36301 | — |
| Bausch Site 129 | Chandler | Arizona | 85224 | — |
| Bausch Site 103 | Peoria | Arizona | 85381 | — |
| Bausch Site 180 | Phoenix | Arizona | 85013 | — |
| Bausch Site 153 | Phoenix | Arizona | 85054 | — |
| Bausch Site 248 | Tempe | Arizona | 85283 | — |
| Bausch Site 222 | Tucson | Arizona | 85712 | — |
| Bausch Site 150 | Little Rock | Arkansas | 77205 | — |
| Bausch Site 164 | Bakersfield | California | 93309 | — |
| Bausch Site 196 | Chula Vista | California | 91910 | — |
| Bausch Site 226 | Chula Vista | California | 91910 | — |
| Bausch Site 174 | Escondido | California | 92025 | — |
| Bausch Site 163 | Fresno | California | 93701 | — |
| Bausch Site 242 | Garden Grove | California | 92844 | — |
| Bausch Site 115 | La Jolla | California | 92037 | — |
| Bausch Site 141 | Lancaster | California | 93534 | — |
| Bausch Site 140 | Los Angeles | California | 90033 | — |
| Bausch Site 189 | Los Angeles | California | 90095 | — |
| Bausch Site 227 | Orange | California | 92868 | — |
| Bausch Site 199 | Pasadena | California | 91105 | — |
| Bausch Site 119 | Redwood City | California | 94063 | — |
| Bausch Site 102 | Rialto | California | 92377 | — |
| Bausch Site 177 | San Diego | California | 92114 | — |
| Bausch Site 171 | San Francisco | California | 94109 | — |
| Bausch Site 214 | San Jose | California | 95116 | — |
| Bausch Site 183 | Upland | California | 91786 | — |
| Bausch Site 143 | Englewood | Colorado | 80113 | — |
| Bausch Site 212 | Littleton | Colorado | 80120 | — |
| Bausch Site 151 | Bristol | Connecticut | 06010 | — |
| Bausch Site 220 | Bradenton | Florida | 34208 | — |
| Bausch Site 257 | Cape Coral | Florida | 33914 | — |
| Bausch Site 197 | Cutler Bay | Florida | 33157 | — |
| Bausch Site 249 | Fort Myers | Florida | 33907 | — |
| Bausch Site 173 | Hialeah | Florida | 33012 | — |
| Bausch Site 238 | Hialeah Gardens | Florida | 33016 | — |
| Bausch Site 235 | Hollywood | Florida | 33024 | — |
| Bausch Site 211 | Homestead | Florida | 33032 | — |
| Bausch Site 139 | Inverness | Florida | 34452 | — |
| Bausch Site 138 | Jacksonville | Florida | 32256 | — |
| Bausch Site 241 | Lakewood Rch | Florida | 34211 | — |
| Bausch Site 157 | Miami | Florida | 33032 | — |
| Bausch Site 255 | Miami | Florida | 33126 | — |
| Bausch Site 263 | Miami | Florida | 33144 | — |
| Bausch Site 264 | Miami | Florida | 33144 | — |
| Bausch Site 268 | Miami | Florida | 33145 | — |
| Bausch Site 224 | Miami | Florida | 33155 | — |
| Bausch Site 243 | Miami | Florida | 33156 | — |
| Bausch Site 166 | Miami | Florida | 33165 | — |
| Bausch Site 244 | Miami | Florida | 33173 | — |
| Bausch Site 266 | Miami | Florida | 33174 | — |
| Bausch Site 147 | Miami | Florida | 33176 | — |
| Bausch Site 218 | Miami | Florida | 33176 | — |
| Bausch Site 240 | Miami | Florida | 33176 | — |
| Bausch Site 186 | New Port Richey | Florida | 34653 | — |
| Bausch Site 213 | Orlando | Florida | 32803 | — |
| Bausch Site 267 | Pembroke Pines | Florida | 33027 | — |
| Bausch Site 256 | Plantation | Florida | 33317 | — |
| Bausch Site 272 | Venice | Florida | 34285 | — |
| Bausch Site 188 | Weston | Florida | 33331 | — |
| Bausch Site 219 | Atlanta | Georgia | 30342 | — |
| Bausch Site 215 | Augusta | Georgia | 30904 | — |
| Bausch Site 260 | Dalton | Georgia | 30720 | — |
| Bausch Site 126 | Marietta | Georgia | 30060 | — |
| Bausch Site 194 | Chicago | Illinois | 60612 | — |
| Bausch Site 120 | Indianapolis | Indiana | 46202 | — |
| Bausch Site 152 | Clive | Iowa | 50325 | — |
| Bausch Site 135 | Iowa City | Iowa | 52242 | — |
| Bausch Site 128 | Topeka | Kansas | 66606 | — |
| Bausch Site 124 | Louisville | Kentucky | 40202 | — |
| Bausch Site 237 | Baton Rouge | Louisiana | 70836 | — |
| Bausch Site 261 | Houma | Louisiana | 70363 | — |
| Bausch Site 134 | Marrero | Louisiana | 70072 | — |
| Bausch Site 118 | New Orleans | Louisiana | 70112 | — |
| Bausch Site 117 | Baltimore | Maryland | 21202 | — |
| Bausch Site 230 | Glen Burnie | Maryland | 21061 | — |
| Bausch Site 132 | Boston | Massachusetts | 02111 | — |
| Bausch Site 161 | Boston | Massachusetts | 02114 | — |
| Bausch Site 223 | Boston | Massachusetts | 02215 | — |
| Bausch Site 146 | Burlington | Massachusetts | 01805 | — |
| Bausch Site 233 | New Bedford | Massachusetts | 02740 | — |
| Bausch Site 136 | Ann Arbor | Michigan | 48109 | — |
| Bausch Site 265 | Detroit | Michigan | 48201 | — |
| Bausch Site 137 | Detroit | Michigan | 48202 | — |
| Bausch Site 149 | Wyoming | Michigan | 49519 | — |
| Bausch Site 253 | Minneapolis | Minnesota | 55413 | — |
| Bausch Site 271 | Minneapolis | Minnesota | 55413 | — |
| Bausch Site 148 | Jackson | Mississippi | 39216 | — |
| Bausch Site 178 | Kansas City | Missouri | 64131 | — |
| Bausch Site 251 | East Brunswick | New Jersey | 08816 | — |
| Bausch Site 191 | Newark | New Jersey | 07103 | — |
| Bausch Site 216 | Albuquerque | New Mexico | 87109 | — |
| Bausch Site 109 | New York | New York | 10021 | — |
| Bausch Site 225 | New York | New York | 10029 | — |
| Bausch Site 116 | New York | New York | 10032 | — |
| Bausch Site 217 | Charlotte | North Carolina | 28204 | — |
| Bausch Site 192 | Durham | North Carolina | 22710 | — |
| Bausch Site 269 | Statesville | North Carolina | 28635 | — |
| Bausch Site 245 | Wilmington | North Carolina | 28401 | — |
| Bausch Site 273 | Wilmington | North Carolina | 28401 | — |
| Bausch Site 114 | Cleveland | Ohio | 44106 | — |
| Bausch Site 154 | Columbus | Ohio | 43210 | — |
| Bausch Site 167 | Dayton | Ohio | 45415 | — |
| Bausch Site 185 | Mentor | Ohio | 44060 | — |
| Bausch Site 270 | Moore | Oklahoma | 73160 | — |
| Bausch Site 110 | Philadelphia | Pennsylvania | 19104 | — |
| Bausch Site 228 | Pittsburgh | Pennsylvania | 15213 | — |
| Bausch Site 250 | Sayre | Pennsylvania | 18840 | — |
| Bausch Site 104 | Charleston | South Carolina | 29425 | — |
| Bausch Site 184 | Johnson City | Tennessee | 37601 | — |
| Bausch Site 181 | Nashville | Tennessee | 37212 | — |
| Bausch Site 221 | Austin | Texas | 78750 | — |
| Bausch Site 122 | Dallas | Texas | 75024 | — |
| Bausch Site 144 | Dallas | Texas | 75203 | — |
| Bausch Site 133 | Dallas | Texas | 75216 | — |
| Bausch Site 107 | Dallas | Texas | 75246 | — |
| Bausch Site 123 | Denison | Texas | 75020 | — |
| Bausch Site 198 | El Paso | Texas | 79936 | — |
| Bausch Site 172 | Fort Worth | Texas | 76104 | — |
| Bausch Site 210 | Fort Worth | Texas | 76104 | — |
| Bausch Site 258 | Harlingen | Texas | 78550 | — |
| Bausch Site 170 | Houston | Texas | 77024 | — |
| Bausch Site 130 | Houston | Texas | 77030 | — |
| Bausch Site 158 | Houston | Texas | 77030 | — |
| Bausch Site 159 | Houston | Texas | 77030 | — |
| Bausch Site 229 | Houston | Texas | 77094 | — |
| Bausch Site 239 | Houston | Texas | 77099 | — |
| Bausch Site 252 | Mesquite | Texas | 75149 | — |
| Bausch Site 195 | Pearland | Texas | 77584 | — |
| Bausch Site 247 | Sugar Land | Texas | 77479 | — |
| Bausch Site 262 | Sugar Land | Texas | 77479 | — |
| Bausch Site 246 | Texas City | Texas | 77591 | — |
| Bausch Site 193 | Waco | Texas | 76710 | — |
| Bausch Site 127 | Murray | Utah | 84121 | — |
| Bausch Site 231 | Manassas | Virginia | 20110 | — |
| Bausch Site 175 | Norfolk | Virginia | 23502 | — |
| Bausch Site 113 | Richmond | Virginia | 23249 | — |
| Bausch Site 111 | Richmond | Virginia | 23298 | — |
| Bausch Site 155 | Seattle | Washington | 98195 | — |
| Bausch Site 105 | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05071716, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 24, 2025 · Synced Oct 29, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05071716 live on ClinicalTrials.gov.