Intensity Modulated Proton or X-Ray Therapy After Surgery for Treatment of Head and Neck Cancer, the HEADLIGHT Study
Public ClinicalTrials.gov record NCT05075980. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
HEADLIGHT: Hypofractionated Proton Therapy for Head and Neck Cancers
Study identification
- NCT ID
- NCT05075980
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Mayo Clinic
- Other
- Enrollment
- 174 participants
Conditions and interventions
Conditions
- Cutaneous Squamous Cell Carcinoma of the Head and Neck
- Head and Neck Carcinoma
- Head and Neck Carcinoma of Unknown Primary
- Hypopharyngeal Carcinoma
- Laryngeal Carcinoma
- Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck
- Metastatic Malignant Neoplasm in the Lymph Nodes
- Nasal Cavity Carcinoma
- Oral Cavity Carcinoma
- Oropharyngeal Carcinoma
- Paranasal Sinus Carcinoma
- Salivary Gland Carcinoma
Interventions
- Biospecimen Collection Procedure
- Cisplatin Drug
- Computed Tomography Procedure
- Intensity-Modulated Proton Therapy Procedure
- Intensity-Modulated Radiation Therapy Radiation
- Magnetic Resonance Imaging Procedure
- Positron Emission Tomography Procedure
- Quality-of-Life Assessment Other
- Questionnaire Administration Other
Procedure · Drug · Radiation + 1 more
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 15, 2022
- Primary completion
- Nov 14, 2027
- Completion
- Nov 14, 2035
- Last update posted
- Apr 12, 2026
2022 – 2035
United States locations
- U.S. sites
- 9
- U.S. states
- 4
- U.S. cities
- 9
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic Hospital in Arizona | Phoenix | Arizona | 85054 | — |
| Mayo Clinic in Arizona | Scottsdale | Arizona | 85259 | — |
| Mayo Clinic in Florida | Jacksonville | Florida | 32224 | — |
| Mayo Clinic Health System in Albert Lea | Albert Lea | Minnesota | 56007 | — |
| Mayo Clinic Health System - Mankato | Mankato | Minnesota | 56001 | — |
| Mayo Clinic Radiation Therapy - Northfield | Northfield | Minnesota | 55057 | — |
| Mayo Clinic in Rochester | Rochester | Minnesota | 55905 | — |
| Mayo Clinic Health System - Eau Claire | Eau Claire | Wisconsin | 54701 | — |
| Mayo Clinic Health System - Franciscan Healthcare | La Crosse | Wisconsin | 54601 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05075980, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 12, 2026 · Synced May 20, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05075980 live on ClinicalTrials.gov.