ClinicalTrials.gov record
Completed Phase 2 Interventional

ML-004 in Adolescents and Adults With Autism Spectrum Disorders (ASD)

ClinicalTrials.gov ID: NCT05081245

Public ClinicalTrials.gov record NCT05081245. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 20, 2026, 11:20 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Parallel Group, Placebo-controlled Study to Investigate the Efficacy, Safety, and Tolerability of ML-004 in Adolescents and Adults With Autism Spectrum Disorders (ASD).

Study identification

NCT ID
NCT05081245
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
MapLight Therapeutics
Industry
Enrollment
168 participants

Conditions and interventions

Interventions

  • ML-004 (IR)/(ER) tablet Drug
  • ML-004 Placebo Drug

Drug

Eligibility (public fields only)

Age range
12 Years to 45 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 12, 2022
Primary completion
Mar 9, 2026
Completion
Apr 16, 2026
Last update posted
May 18, 2026

2022 – 2026

United States locations

U.S. sites
24
U.S. states
15
U.S. cities
24
Facility City State ZIP Site status
Harmonex Neuroscience Research Dothan Alabama 36303
Southwest Autism Research & Resource Center, Clinical Research Phoenix Arizona 85006
Cortica Healthcare Glendale California 91203
NRC Research Institute Orange California 92868
Cortica San Rafael California 94903
Yale Child Study Center New Haven Connecticut 06519
Children's National Health System - The Children's Research Institute (CRI) Washington D.C. District of Columbia 20010
Abba Medical Group Miami Florida 33176
APG Research, LLC Orlando Florida 32803
University of South Florida Psychiatry and Behavioral Neurosciences Tampa Florida 33613
Neurobehavioral Medicine Group Bloomfield Hills Michigan 48302
University of Missouri, Thompson Center for Autism & Neurodevelopmental Disorders Columbia Missouri 65211
Jersey Shore University Medical Center Neptune City New Jersey 07753
Nathan Kline Institute for Psychiatric Research Orangeburg New York 10962
Richmond Behavioral Associates Staten Island New York 10314
Center for Autism and the Developing Brain, New York State Psychiatric Institute White Plains New York 10605
Ohio State University Nisonger Center Columbus Ohio 43210
Suburban Research Associates Media Pennsylvania 19063
BioBehavioral Research of Austin Austin Texas 78759
Red Oak Psychiatry Associates, PA Houston Texas 77090
Road Runner Research, Ltd. San Antonio Texas 78249
Family Psychiatry of The Woodlands The Woodlands Texas 77381
Cedar Clinical Research Draper Utah 84020
Virginia Commonwealth University Richmond Virginia 23220

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05081245, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 18, 2026 · Synced May 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05081245 live on ClinicalTrials.gov.

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