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Active, not recruiting Phase 2 Interventional Results available

A Study of Lu AF82422 in Participants With Multiple System Atrophy

ClinicalTrials.gov ID: NCT05104476

Public ClinicalTrials.gov record NCT05104476. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 22, 2026, 10:03 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Interventional, Randomized, Double-blind, Parallel-group, Placebo-controlled, Multi-centre Study to Assess the Efficacy, Safety and Tolerability of Lu AF82422 in Patients With Multiple System Atrophy

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

To find out the effect of Lu AF82422 on disease progression in participants with multiple system atrophy.

Study identification

NCT ID
NCT05104476
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
H. Lundbeck A/S
Industry
Enrollment
64 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
40 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 16, 2021 (Actual)
Primary completion
Nov 16, 2023 (Actual)
Completion
Mar 7, 2028 (Estimated)
Last update posted
Apr 13, 2026

2021 – 2028

United States locations

U.S. sites
16
U.S. states
9
U.S. cities
15
Facility City State ZIP Site status
The Parkinsons and Movement Disorder Institute Fountain Valley California 92708 —
University of California - San Diego La Jolla California 92037 —
University of California, San Francisco Neurosciences Clinical Research Unit San Francisco California 94158 —
CenExel Rocky Mountain Clinical Research, LLC Englewood Colorado 80113 —
Parkinson's Disease And Movement Disorder Center Of Boca Raton Boca Raton Florida 33486 —
University of Florida Norman Fixel Institute for Neurological Diseases Gainesville Florida 32608 —
Rush University Medical Center, Rush University Cancer Center Chicago Illinois 60612 —
Endeavor Health - Glenbrook Hospital Glenview Illinois 60026 —
Beth Israel Deaconess Medical Center Boston Massachusetts 02215 —
Mayo Clinic Rochester Minnesota 55905 —
University Nebraska Medical Center Omaha Nebraska 68198-8440 —
NYU Langone Health Medical Center New York New York 10016 —
Columbia University Medical Center - The Neurological Institute of New York New York New York 10032 —
Penn State Milton S. Hershey Medical Center - Penn State Hershey Neuroscience Institute (PSHNI) Hershey Pennsylvania 17033 —
University of Pennsylvania Philadelphia Pennsylvania 19107 —
University Of Pittsburgh Pittsburgh Pennsylvania 15213 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05104476, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 13, 2026 · Synced Oct 22, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05104476 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →