A Study of Lu AF82422 in Participants With Multiple System Atrophy

ClinicalTrials.gov ID: NCT05104476

Public ClinicalTrials.gov record NCT05104476. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 18, 2026, 5:27 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Interventional, Randomized, Double-blind, Parallel-group, Placebo-controlled, Multi-centre Study to Assess the Efficacy, Safety and Tolerability of Lu AF82422 in Patients With Multiple System Atrophy

Study identification

NCT ID: NCT05104476
Recruitment status: Active, not recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: H. Lundbeck A/S; Industry
Enrollment: 64 participants

Conditions and interventions

Conditions

Multiple System Atrophy

Interventions

Lu AF82422 Drug
Placebo Drug

Drug

Eligibility (public fields only)

Age range: 40 Years to 75 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Nov 15, 2021
Primary completion: Nov 15, 2023
Completion: Mar 6, 2028
Last update posted: Apr 12, 2026

2021 – 2028

United States locations

U.S. sites: 16
U.S. states: 9
U.S. cities: 15

Facility	City	State	ZIP	Site status
The Parkinsons and Movement Disorder Institute	Fountain Valley	California	92708	—
University of California - San Diego	La Jolla	California	92037	—
University of California, San Francisco Neurosciences Clinical Research Unit	San Francisco	California	94158	—
CenExel Rocky Mountain Clinical Research, LLC	Englewood	Colorado	80113	—
Parkinson's Disease And Movement Disorder Center Of Boca Raton	Boca Raton	Florida	33486	—
University of Florida Norman Fixel Institute for Neurological Diseases	Gainesville	Florida	32608	—
Rush University Medical Center, Rush University Cancer Center	Chicago	Illinois	60612	—
Endeavor Health - Glenbrook Hospital	Glenview	Illinois	60026	—
Beth Israel Deaconess Medical Center	Boston	Massachusetts	02215	—
Mayo Clinic	Rochester	Minnesota	55905	—
University Nebraska Medical Center	Omaha	Nebraska	68198-8440	—
NYU Langone Health Medical Center	New York	New York	10016	—
Columbia University Medical Center - The Neurological Institute of New York	New York	New York	10032	—
Penn State Milton S. Hershey Medical Center - Penn State Hershey Neuroscience Institute (PSHNI)	Hershey	Pennsylvania	17033	—
University of Pennsylvania	Philadelphia	Pennsylvania	19107	—
University Of Pittsburgh	Pittsburgh	Pennsylvania	15213	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05104476, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 12, 2026 · Synced May 18, 2026

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The complete protocol, eligibility criteria, and contact information for NCT05104476 live on ClinicalTrials.gov.

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