Bemarituzumab Plus Chemotherapy and Nivolumab Versus Chemotherapy and Nivolumab for FGFR2b Overexpressed Untreated Advanced Gastric and Gastroesophageal Junction Cancer.
Public ClinicalTrials.gov record NCT05111626. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1b/3 Study of Bemarituzumab Plus Chemotherapy and Nivolumab Versus Chemotherapy and Nivolumab Alone in Subjects With Previously Untreated Advanced Gastric and Gastroesophageal Junction Cancer With FGFR2b Overexpression
Study identification
- NCT ID
- NCT05111626
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Amgen
- Industry
- Enrollment
- 515 participants
Conditions and interventions
Interventions
- Bemarituzumab Drug
- Chemotherapy Drug
- Nivolumab Drug
- Placebo Other
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years to 100 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 13, 2022
- Primary completion
- Oct 13, 2025
- Completion
- Jan 28, 2027
- Last update posted
- Dec 14, 2025
2022 – 2027
United States locations
- U.S. sites
- 37
- U.S. states
- 20
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic - Arizona | Phoenix | Arizona | 85054 | — |
| The Oncology Institute Clinical Research | Cerritos | California | 90703 | — |
| Cancer and Blood Specialty Clinic | Downey | California | 90241 | — |
| City of Hope National Medical Center | Duarte | California | 91010 | — |
| University of California Los Angeles | Los Angeles | California | 90095 | — |
| University of California Irvine | Orange | California | 92868 | — |
| Torrance Memorial Physician Network | Redondo Beach | California | 90277 | — |
| Translational Research in Oncology - US Inc | Santa Monica | California | 90404 | — |
| Translational Research in Oncology US Inc, Trio Central Pharmacy | Santa Monica | California | 90404 | — |
| Olive View-University of California in Los Angeles Medical Center | Sylmar | California | 91342 | — |
| Presbyterian Intercommunity Hospital Health Whitter Hospital | Whittier | California | 90602 | — |
| Yale New Haven Hospital Yale Cancer Center | New Haven | Connecticut | 06520 | — |
| Florida Cancer Specialists - Fort Myers | Fort Myers | Florida | 33901 | — |
| Mayo Clinic | Jacksonville | Florida | 32224 | — |
| Adventist Health System/Sunbelt, Inc d/b/a AdventHealth Orlando | Orlando | Florida | 32804 | — |
| Orlando Health Cancer Institute | Orlando | Florida | 32806 | — |
| University of Illinois Chicago | Chicago | Illinois | 60612 | — |
| Greater Baltimore Medical Center | Baltimore | Maryland | 21204 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Summit Medical Group | Florham Park | New Jersey | 07932 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10022 | — |
| Stony Brook University Medical Center | Stony Brook | New York | 11794-7263 | — |
| FirstHealth Cancer Center | Pinehurst | North Carolina | 28374 | — |
| Gabrail Cancer Center, LLC | Canton | Ohio | 44718 | — |
| Providence Cancer Institute Franz Clinic | Portland | Oregon | 97213 | — |
| Saint Lukes University Health Network | Allentown | Pennsylvania | 18104 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| West Cancer Center | Germantown | Tennessee | 38138 | — |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | — |
| Texas Oncology Central-South | Austin | Texas | 78705 | — |
| University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| United States Oncology Regulatory Affairs Corporate Office | The Woodlands | Texas | 77380 | — |
| US Oncology Research Investigational Products Center | The Woodlands | Texas | 77380 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
| Northwest Cancer Specialists - Vancouver | Vancouver | Washington | 98684 | — |
| Aurora Health Care Metro Inc | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 311 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05111626, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 14, 2025 · Synced Apr 29, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05111626 live on ClinicalTrials.gov.