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Terminated Phase 2Phase 3 Interventional

Efficacy and Safety of REC-2282 in Patients With Progressive Neurofibromatosis Type 2 (NF2) Mutated Meningiomas

ClinicalTrials.gov ID: NCT05130866

Public ClinicalTrials.gov record NCT05130866. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 6:24 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Two-staged, Phase 2/3, Randomized, Multicenter Study to Evaluate the Efficacy and Safety of REC-2282 in Participants With Progressive NF2 Mutated Meningiomas

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a two-staged, Phase 2/3, randomized, multi-center study to investigate the efficacy and safety of REC-2282 in participants with progressive NF2 mutated meningiomas.

Study identification

NCT ID
NCT05130866
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
Recursion Pharmaceuticals Inc.
Industry
Enrollment
25 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
12 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 20, 2022 (Actual)
Primary completion
Aug 18, 2025 (Actual)
Completion
Aug 18, 2025 (Actual)
Last update posted
Aug 17, 2026

2022 – 2025

United States locations

U.S. sites
14
U.S. states
9
U.S. cities
11
Facility City State ZIP Site status
House Institute Los Angeles California 90057 —
University of California Los Angeles Los Angeles California 90095 —
Children's National Hospital Washington D.C. District of Columbia 20010 —
University of Florida Gainesville Florida 32611 —
Nicklaus Children's Hospital Miami Florida 33155 —
Sarah Cannon Cancer Institute - HCA Midwest Overland Park Kansas 66211 —
Massachusetts General Hospital Boston Massachusetts 02114 —
Beth Israel Deaconess Medical Center Boston Massachusetts 02215 —
University of Minnesota / Masonic Cancer Center Minneapolis Minnesota 55455 —
Mayo Clinic Rochester Minnesota 55905 —
Columbia University New York New York 10032 —
Memorial Sloan Kettering Cancer Center New York New York 10065 —
Duke University Medical Center Durham North Carolina 27710 —
UT Southwestern Medical Center Dallas Texas 75390 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05130866, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 17, 2026 · Synced Oct 21, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05130866 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →