A Study to Evaluate the Efficacy and Safety of DA-1229 (Evogliptin) in Patient's Calcific Aortic Valve Disease With Mild to Moderate Aortic Stenosis (EVOID-AS)
Public ClinicalTrials.gov record NCT05143177. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Adaptive Phase 2/3 Multicenter, Double-Blind, Placebo-Controlled, Randomized, Parallel, 2 Arm Study to Evaluate the Efficacy and Safety of DA-1229 (Evogliptin) in Patient's Calcific Aortic Valve Disease With Mild to Moderate Aortic Stenosis (EVOID-AS)
Study identification
- NCT ID
- NCT05143177
- Recruitment status
- Suspended
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Lead sponsor
- REDNVIA Co., Ltd.
- Industry
- Enrollment
- 580 participants
Conditions and interventions
Conditions
Interventions
- Evogliptin Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 35 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 26, 2022
- Primary completion
- May 14, 2026
- Completion
- Dec 29, 2026
- Last update posted
- Mar 26, 2026
2022 – 2026
United States locations
- U.S. sites
- 24
- U.S. states
- 17
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic, AZ | Phoenix | Arizona | 85054 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| University of Colorado | Aurora | Colorado | 80045 | — |
| Mayo Clinic, FL | Jacksonville | Florida | 32224 | — |
| Baycare Health systems | Safety Harbor | Florida | 34695 | — |
| Northside Hospital | Atlanta | Georgia | 30342 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Beaumont Hospital, Royal Oak | Royal Oak | Michigan | 48073 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Hackensack Meridian Health | Hackensack | New Jersey | 07601 | — |
| Rutgers- Robert Wood Johnson Medical School | New Brunswick | New Jersey | 08901 | — |
| Ichan School of Medicine | New York | New York | 10025 | — |
| Stony brook | Stony Brook | New York | 11974 | — |
| Christ Hospital | Cincinnati | Ohio | 45219 | — |
| OhioHealth Research Institute | Columbus | Ohio | 43214 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| University of Pittsburgh Medical Center | Mechanicsburg | Pennsylvania | 17050 | — |
| Einstein Medical Center Philadelphia | Philadelphia | Pennsylvania | 19141 | — |
| Texas Heart Institute | Houston | Texas | 77030 | — |
| The University of Vermont Medical Center | Burlington | Vermont | 05401 | — |
| Inova Health Care Services | Falls Church | Virginia | 22042 | — |
| Aurora Research Institute | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05143177, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 26, 2026 · Synced May 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05143177 live on ClinicalTrials.gov.