Randomized Trial Comparing Immediate vs. Deferred Surgery for Symptomatic ERM

ClinicalTrials.gov ID: NCT05145491

Public ClinicalTrials.gov record NCT05145491. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 20, 2026, 6:46 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Randomized Trial Comparing Immediate Versus Deferred Surgery for Symptomatic Epiretinal Membranes

Study identification

NCT ID: NCT05145491
Recruitment status: Recruiting
Study type: Interventional
Phase: Not applicable
Lead sponsor: Jaeb Center for Health Research; Other
Enrollment: 400 participants

Conditions and interventions

Conditions

Epiretinal Membrane

Interventions

Deferred Vitrectomy Procedure
Immediate Vitrectomy Procedure

Procedure

Eligibility (public fields only)

Age range: 50 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Feb 21, 2022
Primary completion: Dec 30, 2026
Completion: Dec 30, 2026
Last update posted: Jan 27, 2026

2022 – 2026

United States locations

U.S. sites: 45
U.S. states: 22
U.S. cities: 43

Facility	City	State	ZIP	Site status
Mayo Clinic Arizona	Scottsdale	Arizona	85259	Recruiting
Kent W. Small, MD, AMC	Glendale	California	91203-1971	Recruiting
Salehi Retina Institute Inc.	Huntington Beach	California	92647-8693	Recruiting
Loma Linda University	Loma Linda	California	92354	Recruiting
Retina Vitreous Associates, Northern California Retina Vitreous Assoc Medical Group, Inc.	Mountain View	California	94040-4123	Recruiting
East Bay Retina Consultants, Inc.	Oakland	California	94609-3028	Recruiting
Regents of the University of California, Davis, DBA University of California, Davis	Sacramento	California	95817	Recruiting
Macula Retina Vitreous Institute	Torrance	California	90503	Recruiting
Florida Retina Institute, James A. Staman, MD, PA- Jacksonville	Jacksonville	Florida	32216	Recruiting
Sarasota Retina Institute	Sarasota	Florida	34239	Recruiting
SEASHORE RETINA LLC DBA Retina Specialists of Tampa	Wesley Chapel	Florida	33544	Recruiting
Southeast Retina Center, P.C.	Augusta	Georgia	30909	Recruiting
Thomas Eye Group	Sandy Springs	Georgia	30328	Recruiting
Northwestern University	Chicago	Illinois	60611	Recruiting
Rush University Medical Center	Chicago	Illinois	60612	Recruiting
Illinois Retina Associates SC - Oak Park Site	Oak Park	Illinois	60304	Recruiting
Raj K. Maturi, M.D., P.C.	Indianapolis	Indiana	46290	Recruiting
Mid-America Retina Consultants, P.A.	Overland Park	Kansas	66211	Recruiting
University of Kansas Medical Center Research Institute, Inc.	Prairie Village	Kansas	66208	Recruiting
Joseph E. Humble and Raymond Haik PTRS DBA Eye Assoc of Northeast Louisiana	West Monroe	Louisiana	71291-4452	Recruiting
Elman Retina Group, P.A.	Baltimore	Maryland	21237	Recruiting
Johns Hopkins University	Baltimore	Maryland	21287	Recruiting
Valley Eye Physicians and Surgeons	Ayer	Massachusetts	01432	Recruiting
Joslin Diabetes Center	Boston	Massachusetts	02215	Recruiting
Retina Associates of Michigan	Grand Blanc	Michigan	48439	Recruiting
The Curators of the University of Missouri	Columbia	Missouri	65201-5276	Recruiting
Retina Research Institute, LLC	St Louis	Missouri	63128-1729	Recruiting
Retina-Vitreous Surgeons of Central NY, PC	Liverpool	New York	13088	Recruiting
Retina Associates of Western NY, P.C.	Rochester	New York	14620-4655	Recruiting
University of North Carolina at Chapel Hill	Chapel Hill	North Carolina	27517	Recruiting
Retina Vitreous Center	Edmond	Oklahoma	73013-9791	Recruiting
Verum Research LLC	Eugene	Oregon	97401	Recruiting
Cascade Medical Research Institute, LLC	Springfield	Oregon	97477	Recruiting
Retina-Vitreous Consultants, Inc.	Monroeville	Pennsylvania	15146	Recruiting
The Trustees of the University of Pennsylvania	Philadelphia	Pennsylvania	19104	Recruiting
Pittsburg Clinical Trial Consortium	Sewickley	Pennsylvania	15143	Recruiting
Hilton Head Retina Institute	Hilton Head Island	South Carolina	29926	Recruiting
Ophthalmology Ltd.	Sioux Falls	South Dakota	57108	Recruiting
Vanderbilt Eye Institute	Nashville	Tennessee	37232	Recruiting
Austin Research Center for Retina	Austin	Texas	78705	Recruiting
Retina Consultants of Texas	Bellaire	Texas	77401	Recruiting
Baylor College of Medicine, Baylor Eye Physicians and Surgeons	Houston	Texas	77030	Recruiting
Texas Retina Associates	Lubbock	Texas	79424	Recruiting
Retinal Consultants of San Antonio	San Antonio	Texas	78240	Recruiting
Spokane Eye Clinical Research, PLLC	Spokane	Washington	99204	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05145491, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jan 27, 2026 · Synced May 20, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05145491 live on ClinicalTrials.gov.

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