RNS System NAUTILUS Study
Public ClinicalTrials.gov record NCT05147571. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
RNS® System Responsive Thalamic Stimulation for Primary Generalized Seizures (NAUTILUS) Study
Study identification
- NCT ID
- NCT05147571
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- NeuroPace
- Industry
- Enrollment
- 100 participants
Conditions and interventions
Interventions
- Responsive stimulation Device
- Sham stimulation Device
Device
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 8, 2022
- Primary completion
- Apr 3, 2025
- Completion
- Feb 28, 2026
- Last update posted
- Jul 8, 2025
2022 – 2026
United States locations
- U.S. sites
- 23
- U.S. states
- 19
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Mayo Clinic - Arizona | Phoenix | Arizona | 85054 | — |
| University of Colorado | Aurora | Colorado | 80045 | — |
| Nicklaus Children's Hospital | Miami | Florida | 33155 | — |
| University of South Florida | Tampa | Florida | 33606 | — |
| Indiana University Health | Indianapolis | Indiana | 46202 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Spectrum Health Butterworth Hospital | Grand Rapids | Michigan | 48503 | — |
| Mayo Clinic - Rochester | Rochester | Minnesota | 55902 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| Mary Hitchcock Memorial Hospital (Dartmouth) | Lebanon | New Hampshire | 03756 | — |
| University of New Mexico | Albuquerque | New Mexico | 87131 | — |
| New York University Langone | New York | New York | 10016 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| UPMC | Pittsburgh | Pennsylvania | 15213 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| The University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| University of Utah Healthcare | Salt Lake City | Utah | 84132 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05147571, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 8, 2025 · Synced May 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05147571 live on ClinicalTrials.gov.