A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189, in 10- to 30-Year-Old Healthy Adolescents and Adults
Public ClinicalTrials.gov record NCT05164094. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2, Randomized, Observer-Blind, Placebo-Controlled, Dose-Ranging Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189, in 10- to 30-Year-Old Healthy Adolescents and Adults
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main objective of Part A of this trial is to evaluate the safety and reactogenicity of mRNA-1189 in 18- to 30-year-old healthy adults, the main objective of Part B is to evaluate the safety and reactogenicity of mRNA-1189 in 12- to \<18-year-old healthy EBV-seronegative adolescents, and the main objective of Part C is to evaluate the safety and reactogenicity of mRNA-1189 in 10- to 21-year-old healthy adolescents and adults.
Study identification
- NCT ID
- NCT05164094
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 867 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 10 Years to 30 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 28, 2021 (Actual)
- Primary completion
- Oct 5, 2026 (Estimated)
- Completion
- Aug 18, 2027 (Estimated)
- Last update posted
- May 6, 2026
2021 – 2027
United States locations
- U.S. sites
- 65
- U.S. states
- 25
- U.S. cities
- 59
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Medical Affiliated Research Institute | Huntsville | Alabama | 35801 | — |
| Smart Cures Clinical Research | Anaheim | California | 92806 | — |
| Benchmark Research - Colton - HyperCore - PPDS | Colton | California | 92324 | — |
| Fomat Medical Research | Oxnard | California | 93030 | — |
| Center For Clinical Trials LLC -Paramount | Paramount | California | 90723-5459 | — |
| Artemis Institute For Clinical Research LLC - Riverside - Headlands - PPDS | Riverside | California | 92503 | — |
| Peninsula Research Associates - Headlands Research - PPDS | Rolling Hills | California | 90274 | — |
| Velocity Clinical Research - Banning - PPDS | San Bernardino | California | 92220-3082 | — |
| Acclaim Clinical Research | San Diego | California | 92120 | — |
| California Research Foundation - 4180 Ruffin Rd | San Diego | California | 92123-1881 | — |
| Orange County Research Center | Tustin | California | 92780 | — |
| CenExel iResearch, LLC | Hollywood | Florida | 33024 | — |
| Jacksonville Center For Clinical Research - ERN - PPDS | Jacksonville | Florida | 32216-4357 | — |
| iResearch Savannah - CenExel - PPDS | Savannah | Georgia | 31405 | — |
| Velocity Clinical Research - Savannah | Savannah | Georgia | 31406 | — |
| Clinical Research Atlanta - Headlands - PPDS | Stockbridge | Georgia | 30281-9054 | — |
| Velocity Clinical Research | Meridian | Idaho | 83642 | — |
| Olivo Medical and Wellness Center | Chicago | Illinois | 60618-8101 | — |
| DM Clinical Research | River Forest | Illinois | 60305 | — |
| Velocity Clinical Research | Valparaiso | Indiana | 46383 | — |
| Velocity Clinical Research - Sioux City | Sioux City | Iowa | 51106 | — |
| Alliance for Multispecialty Research, LLC - El Dorado - PPDS | El Dorado | Kansas | 67042-2187 | — |
| Johnson County Clin-Trials | Lenexa | Kansas | 66219 | — |
| Alliance for Multispecialty Research LLC, East Wichita | Wichita | Kansas | 67207 | — |
| Michael W Simon MD, PSC | Lexington | Kentucky | 40517-8379 | — |
| Velocity Clinical Research - Lafayette - PPDS | Lafayette | Louisiana | 70508-5173 | — |
| UMass Memorial Medical Center | Worcester | Massachusetts | 01605 | — |
| Great Lakes Research Institute | Southfield | Michigan | 48075 | — |
| DM Clinical Research | Southfield | Michigan | 48076 | — |
| Clinical Research Institute, Inc. | Minneapolis | Minnesota | 55402 | — |
| Sundance Clinical Research - ERN - PPDS | St Louis | Missouri | 63141 | — |
| Velocity Clinical Research - Grand Island | Grand Island | Nebraska | 68803 | — |
| Velocity Clinical Research - Lincoln | Lincoln | Nebraska | 68510 | — |
| Velocity Clinical Research - Norfolk | Norfolk | Nebraska | 68701 | — |
| Quality Clinical Research - ClinEdge - PPDS | Omaha | Nebraska | 68112 | — |
| Velocity Clinical Research - Omaha | Omaha | Nebraska | 68134 | — |
| Alliance for Multispecialty Research, LLC | Las Vegas | Nevada | 89119 | — |
| Velocity Clinical Research - Binghamton | Binghamton | New York | 13901 | — |
| Velocity Clinical Research | East Syracuse | New York | 13057 | — |
| Velocity Clinical Research - Vestal | Vestal | New York | 13850 | — |
| Lucas Research | Morehead City | North Carolina | 28557 | — |
| Lucas Research | New Bern | North Carolina | 28562 | — |
| Velocity Clinical Research - Cincinnati | Cincinnati | Ohio | 45219 | — |
| Senders Pediatrics | South Euclid | Ohio | 44121 | — |
| Lynn Health Science Institute | Oklahoma City | Oklahoma | 73112 | — |
| Velocity Clinical Research | Anderson | South Carolina | 29621 | — |
| Coastal Pediatric Associates | Charleston | South Carolina | 29414-5834 | — |
| Coastal Carolina Research Center | North Charleston | South Carolina | 29405 | — |
| Benchmark Research - Austin - PPDS | Austin | Texas | 78705 | — |
| Tekton Research - Texas - Platinum - PPDS | Austin | Texas | 78745 | — |
| ACRC Trials - Hunt - PPDS | Carrollton | Texas | 75010 | — |
| Velocity Clinical Research - Austin - PPDS | Cedar Park | Texas | 78613-3936 | — |
| Cedar Health Research - Fort Worth - PPDS | Dallas | Texas | 75251 | — |
| Benchmark Research - Fort Worth - HyperCore - PPDS | Fort Worth | Texas | 76135 | — |
| ACRC Trials | Frisco | Texas | 75024 | — |
| Helios Clinical Research | Houston | Texas | 77008 | — |
| DM Clinical Research - Texas Center For Drug Development - ERN - PPDS | Houston | Texas | 77065 | — |
| ACRC Trials - Legacy Medical Village Headquarters | Plano | Texas | 75024-4174 | — |
| DM Clinical Research - Texas Center For Drug Development - ERN - PPDS | Tomball | Texas | 77375 | — |
| Victoria Clinical Research Group | Victoria | Texas | 77979 | — |
| Tanner Clinic | Layton | Utah | 84041 | — |
| Charlottesville Medical Research Center | Charlottesville | Virginia | 22911 | — |
| Health Research of Hampton Roads Inc. - Newport News | Newport News | Virginia | 23606-4537 | — |
| Alliance for Multispecialty Research, LLC | Norfolk | Virginia | 23502 | — |
| Clinical Research Partners LLC - Richmond - ERN - PPDS | Richmond | Virginia | 23226-3787 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05164094, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 6, 2026 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05164094 live on ClinicalTrials.gov.