ClinicalTrials.gov record
A Study to Evaluate the Efficacy and Safety of Vonoprazan Compared to Placebo for Relief of Heartburn in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease (NERD)
ClinicalTrials.gov ID: NCT05195528
Public ClinicalTrials.gov record NCT05195528. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Multicenter Study to Evaluate the Efficacy and Safety of Vonoprazan 10 and 20 mg Compared to Placebo for Relief of Heartburn in Subjects With Symptomatic Non-Erosive Gastroesophageal Reflux Disease (NERD) After 4 Weeks and to Evaluate the Efficacy and Safety of Vonoprazan 10 and 20 mg for Relief of Heartburn in Subjects With NERD After 6 Months
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objectives of this study are to assess the efficacy of vonoprazan (10 mg and 20 mg once daily \[QD\]) compared to placebo (QD) in relief of heartburn over 4 weeks in participants with NERD.
Study identification
- NCT ID
- NCT05195528
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 776 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 17, 2022 (Actual)
- Primary completion
- Nov 21, 2022 (Actual)
- Completion
- May 17, 2023 (Actual)
- Last update posted
- Dec 29, 2023
2022 – 2023
United States locations
- U.S. sites
- 108
- U.S. states
- 32
- U.S. cities
- 97
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| North Alabama Research Center LLC | Athens | Alabama | 35611-2456 | — |
| Cullman Research Center | Cullman | Alabama | 35055 | — |
| Medical Affiliated Research Center Inc | Huntsville | Alabama | 35801-6002 | — |
| East View Medical Research, LLC | Mobile | Alabama | 36606 | — |
| Elite Clinical Studies - Phoenix - Clinedge | Phoenix | Arizona | 85018-5434 | — |
| Del Sol Research Management - Clinedge | Tucson | Arizona | 85715-3834 | — |
| Preferred Research Partners - ClinEdge | Little Rock | Arkansas | 72211-3868 | — |
| Arkansas Gastroenterology | North Little Rock | Arkansas | 72117-2924 | — |
| Alliance Research Institute | Canoga Park | California | 91304-3862 | — |
| GW Research, Inc | Chula Vista | California | 91910-3906 | — |
| eStudy Site | Chula Vista | California | 91911-6660 | — |
| Kindred Medical Institute for Clinical Trials, LLC | Corona | California | 92879-3124 | — |
| BG Clinical Research | Encinitas | California | 92024 | — |
| Paragon Rx Clinical | Garden Grove | California | 92840-3103 | — |
| OM Research LLC | Lancaster | California | 93534 | — |
| Torrance Clinical Research Institute | Lomita | California | 90717-2101 | — |
| Prospective Research Innovations | Rancho Cucamonga | California | 91730 | — |
| Northern California Research Corp | Sacramento | California | 95821-2640 | — |
| Digestive Care Center | San Carlos | California | 94070-3939 | — |
| Clinical Applications Laboratories Inc | San Diego | California | 92103-5639 | — |
| Medical Associates Research Group, Inc. | San Diego | California | 92123-4207 | — |
| Paragon Rx Clinical, Inc. | Santa Ana | California | 92703-1811 | — |
| Western States Clinical Research Inc | Wheat Ridge | Colorado | 80033-6800 | — |
| Gastroenterology Associates of Fairfield County | Bridgeport | Connecticut | 06606-5301 | — |
| Connecticut Clinical Research Institute | Bristol | Connecticut | 06010-5161 | — |
| Medical Research Center of Connecticut, LLC | Hamden | Connecticut | 06518 | — |
| Velocity Clinical Research - New Smyrna Beach | Edgewater | Florida | 32132-2720 | — |
| Nature Coast Clinical Research | Inverness | Florida | 34452-4717 | — |
| ENCORE Borland-Groover Clinical Research | Jacksonville | Florida | 32256-6004 | — |
| ClinCloud | Maitland | Florida | 32751-5570 | — |
| Legacy Clinical Solutions: Sensible HealthCare, LLC | Ocoee | Florida | 34761-2964 | — |
| Digestive Disease Consultants, PA | Orange Park | Florida | 32073-4752 | — |
| Medical Center | Orlando | Florida | 32807-4346 | — |
| Advanced Gastroenterology Associates, LLC | Palm Harbor | Florida | 34684-2648 | — |
| Precision Clinical Research | Sunrise | Florida | 33351-7311 | — |
| Guardian Angel Research | Tampa | Florida | 33614-2700 | — |
| Southeast Clinical Research Center | Dalton | Georgia | 30720 | — |
| Atlanta Center For Gastroenterology PC | Decatur | Georgia | 30033-6146 | — |
| Gastroenterology Associates of Central Georgia, LLC | Macon | Georgia | 31201-3262 | — |
| Atlanta Center For Clinical Research | Roswell | Georgia | 30075-2456 | — |
| Mount Vernon Clinical Research, LLC | Sandy Springs | Georgia | 30328-4277 | — |
| In Quest Medical Research | Suwanee | Georgia | 30024-9134 | — |
| Treasure Valley Medical Research | Boise | Idaho | 83706-1345 | — |
| Grand Teton Research Group, PLLC | Idaho Falls | Idaho | 83404-7590 | — |
| Iowa Digestive Disease Center | Clive | Iowa | 50325-8151 | — |
| Kansas Medical Clinic | Topeka | Kansas | 66606-1707 | — |
| Clinical Trials Management LLC | Covington | Louisiana | 70433-4966 | — |
| Combined Gastro Research | Lafayette | Louisiana | 70503-2636 | — |
| Tandem Clinical Research, LLC | Marrero | Louisiana | 70072-3151 | — |
| Clinical Trials of America, LLC | West Monroe | Louisiana | 71291-5324 | — |
| Investigative Clinical Research | Annapolis | Maryland | 21401-1091 | — |
| Digestive Health Specialists | Chelmsford | Massachusetts | 01824-2775 | — |
| Gastroenterology Associates of Western Michigan, PLC | Wyoming | Michigan | 49519-9691 | — |
| MNGI Digestive Health | Minneapolis | Minnesota | 55413 | — |
| Minnesota Gastroenterology PA | Plymouth | Minnesota | 55446-3661 | — |
| Clinical Research Professionals | Chesterfield | Missouri | 63005-1248 | — |
| Quality Clinical Research - HyperCore | Omaha | Nebraska | 68114-3723 | — |
| Sierra Clinical Research | Las Vegas | Nevada | 89106-4159 | — |
| Office of Site 1 | Las Vegas | Nevada | 89119-5190 | — |
| Office of Site 2 | Las Vegas | Nevada | 89128-0802 | — |
| Advanced Research Institute | Reno | Nevada | 89511-2060 | — |
| The Gastroenterology Group of Northern NJ LLC | Englewood | New Jersey | 07631-4141 | — |
| Allied Health Clinical Research Organization | Freehold | New Jersey | 07728-2974 | — |
| NY Scientific | Brooklyn | New York | 11235 | — |
| Drug Trials America | Hartsdale | New York | 10530-1837 | — |
| Care Access Research | New York | New York | 10065-8559 | — |
| UNC Medical Center | Chapel Hill | North Carolina | 27514-4220 | — |
| Charlotte Gastroenterology and Hepatology PLLC | Charlotte | North Carolina | 28207-1200 | — |
| Peters Medical Research, LLC | High Point | North Carolina | 27260 | — |
| East Carolina Gastroenterology | Jacksonville | North Carolina | 28546-7325 | — |
| Clinical Trials of America-NC, LLC | Mount Airy | North Carolina | 27030-4459 | — |
| Trial Management Associates LLC | Wilmington | North Carolina | 28403-7018 | — |
| Lillestol Research | Fargo | North Dakota | 58104-4557 | — |
| Gastro Health Research | Cincinnati | Ohio | 45219 | — |
| Remington Davis Clinical Research | Columbus | Ohio | 43215-7098 | — |
| Great Lakes Medical Research LLC | Mentor | Ohio | 44060-6211 | — |
| North Shore Gastroenterology | Westlake | Ohio | 44145-7215 | — |
| Susquehanna Research Group, LLC | Harrisburg | Pennsylvania | 17110-3673 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104-5127 | — |
| Frontier Clinical Research, LLC | Uniontown | Pennsylvania | 15401-9069 | — |
| Velocity Clinical Research - Providence | East Greenwich | Rhode Island | 02818-1762 | — |
| Gastroenterology Associates, PA of Greenville | Greenville | South Carolina | 29615 | — |
| Gastro One | Cordova | Tennessee | 38018 | — |
| Galen Medical Group | Hixson | Tennessee | 37343 | — |
| Clinical Research Associates Inc | Nashville | Tennessee | 37203-2066 | — |
| QUALITY Medical Research | Nashville | Tennessee | 37211-4981 | — |
| Vanderbilt Digestive Disease Center | Nashville | Tennessee | 37232-0028 | — |
| Gastroenterology Consultants of South Texas, PLLC | Brownsville | Texas | 78550 | — |
| Digestive Health Associates of Texas, PA | Carrollton | Texas | 75010-4545 | — |
| Family Medicine Associates of Texas | Carrollton | Texas | 75010 | — |
| Texas Tech Physicians of El Paso | El Paso | Texas | 79905-2707 | — |
| Digestive Health Associates of Texas, P.A.dba DHAT Research Institute | Garland | Texas | 75044-2210 | — |
| Primecare Medical Group | Houston | Texas | 77024-2593 | — |
| Biopharma Informatic, LLC | Houston | Texas | 77084 | — |
| Rio Grande Gastroenterology | McAllen | Texas | 78503 | — |
| Quality Research Inc | San Antonio | Texas | 78209-1744 | — |
| Gastroenterology Research of San Antonio (GERSA) | San Antonio | Texas | 78229-3270 | — |
| Southern Star Research Institute LLC | San Antonio | Texas | 78229-4894 | — |
| Sherman Clinical Research | Sherman | Texas | 75092 | — |
| Texas Digestive Disease Consultants | Southlake | Texas | 76092-9167 | — |
| GI Alliance | Southlake | Texas | 76092 | — |
| Texas Gastro Consultants | Tomball | Texas | 77375-3348 | — |
| Advanced Research Institute | Ogden | Utah | 84405-4928 | — |
| Kalo Clinical Research | Salt Lake City | Utah | 84102 | — |
| Advanced Research Institute | Sandy City | Utah | 84092-4350 | — |
| Blue Ridge Medical Research | Lynchburg | Virginia | 24502-4272 | — |
| Clinical Research Partners LLC | Richmond | Virginia | 23226-3787 | — |
| Washington Gastroenterology | Bellevue | Washington | 98004-4631 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05195528, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 29, 2023 · Synced Nov 1, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05195528 live on ClinicalTrials.gov.