ClinicalTrials.gov record
A Study of Guselkumab Subcutaneous Therapy in Participants With Moderately to Severely Active Crohn's Disease
ClinicalTrials.gov ID: NCT05197049
Public ClinicalTrials.gov record NCT05197049. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
CNTO1959CRD3004: A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Study to Evaluate the Efficacy and Safety of Guselkumab Subcutaneous Induction Therapy in Participants With Moderately to Severely Active Crohn's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy and safety of guselkumab in participants with Crohn's disease.
Study identification
- NCT ID
- NCT05197049
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 350 participants
Conditions and interventions
Conditions
Interventions
- Guselkumab Dose 1 Drug
- Guselkumab Dose 2 Drug
- Guselkumab Dose 3 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 19, 2022 (Actual)
- Primary completion
- Jul 4, 2023 (Actual)
- Completion
- Oct 30, 2028 (Estimated)
- Last update posted
- Sep 25, 2026
2022 – 2028
United States locations
- U.S. sites
- 77
- U.S. states
- 27
- U.S. cities
- 68
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Digestive Health Specialists of the Southeast | Dothan | Alabama | 36305 | — |
| Advanced Gastro P.C | Chandler | Arizona | 85224-1636 | — |
| Reliance Research | Scottsdale | Arizona | 85260 | — |
| Moore Clinical Trials, LLC | Little Rock | Arkansas | 72205-6414 | — |
| Central Arkansas Veterans Healthcare System | Little Rock | Arkansas | 72223 | — |
| Clinnova Research | Anaheim | California | 92805 | — |
| Om Research LLC 1 | Lancaster | California | 93534 | — |
| Om Research LLC | Lancaster | California | 93534 | — |
| United Gastroenterologists | Los Alamitos | California | 90720 | — |
| Paul Wallace MD | Los Angeles | California | 90048 | — |
| Digestive System Healthcare | Pasadena | California | 77505-3950 | — |
| Northshore Gastroenterology Research, LLC | San Diego | California | 92103-2120 | — |
| Clinical Applications Laboratories, Inc | San Diego | California | 92103 | — |
| Santa Maria Gastroenterology | Santa Maria | California | 93454 | — |
| Clinical Research of California | Walnut Creek | California | 94598 | — |
| Amel Med LLC Research | Grand Junction | Colorado | 81505-1027 | — |
| Western Connecticut Health Network/Danbury Hospital | Danbury | Connecticut | 06810 | — |
| Gastroenterology Associates of SW Florida | Clearwater | Florida | 33762-5323 | — |
| Pioneer Research Solutions Inc. | Coconut Creek | Florida | 33066 | — |
| Omega Research Consultants | DeBary | Florida | 32713 | — |
| Harmony Medical Research Institute, Inc. | Hialeah | Florida | 33016 | — |
| Central Florida Gastro Research | Kissimmee | Florida | 34741 | — |
| Community Research Foundation, Inc. | Miami | Florida | 33155 | — |
| Gastroenterology Group Of Naples | Naples | Florida | 34102 | — |
| Center for Digestive Health | Orlando | Florida | 32803-1853 | — |
| Central Florida Internists | Orlando | Florida | 32819 | — |
| Synergy Clinical Research | St. Petersburg | Florida | 33705 | — |
| Atlanta Gastroenterology Specialists, PC | Atlanta | Georgia | 30224 | — |
| Agile Clinical Research Trials, LLC | Atlanta | Georgia | 30328 | — |
| Atlanta Center For Gastroenterology | Decatur | Georgia | 30033 | — |
| Gastroenterolgy Associates of Central GA | Macon | Georgia | 31201 | — |
| Gastroenterology Consultants | Roswell | Georgia | 30076-4943 | — |
| USF Asthma, Allergy, Immunology Clinical Research Unit | Boise | Idaho | 83706 | — |
| Grand Teton Research Group, PLLC | Idaho Falls | Idaho | 83404 | — |
| Lemah Creek Clinical Research | Oakbrook Terrace | Illinois | 60618 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66103-2937 | — |
| BVL Clinical Research | Leawood | Kansas | 66211 | — |
| Cotton O'Neil Digestive Health Center | Topeka | Kansas | 66606 | — |
| Tri-State Gastroenterology Assoc | Crestview Hills | Kentucky | 41017 | — |
| Tandem Clinical Research | Marrero | Louisiana | 70072 | — |
| Institute for Digestive Health and Liver Disease | Baltimore | Maryland | 21202-2102 | — |
| Woodholme Gastroenterology Associates | Glen Burnie | Maryland | 21061 | — |
| Digestive Health Specialists PC | Chelmsford | Massachusetts | 01824 | — |
| FC Research, LLC | South Dartmouth | Massachusetts | 02747 | — |
| Clinical Research Institute of Michigan, LLC | Chesterfield | Michigan | 48047 | — |
| Detroit Clinical Research Center | Livonia | Michigan | 48152 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| SUNY Downstate Medical Center | Brooklyn | New York | 11203 | — |
| Smart Medical Research | Jackson Heights | New York | 11372 | — |
| Crystal Run Healthcare LLP | Middletown | New York | 10941 | — |
| New York Gastroenterology Associates | New York | New York | 10075 | — |
| DiGiovanna Institute for Medical Education & Research | North Massapequa | New York | 11758 | — |
| A1 Clinical Network | Queens | New York | 11375 | — |
| Carolinas Medical Center | Charlotte | North Carolina | 28207 | — |
| Onsite Clinical Solutions | Charlotte | North Carolina | 28277 | — |
| Carolina Research | Greenville | North Carolina | 27834 | — |
| Gastroenterology Associates of the Piedmont, P.A. | Winston-Salem | North Carolina | 27103 | — |
| Central Ohio Endoscopy Center LLC | Columbus | Ohio | 43214 | — |
| Dayton Gastroenterology, Inc | Dayton | Ohio | 45440 | — |
| Great Lakes Gastroenterology | Mentor | Ohio | 44060 | — |
| Oklahoma University Health Science Center | Oklahoma City | Oklahoma | 73104 | — |
| Integris Baptist Office | Oklahoma City | Oklahoma | 73112 | — |
| Central Sooner Research | Oklahoma City | Oklahoma | 73120 | — |
| Essential Medical Research | Tulsa | Oklahoma | 74137-7061 | — |
| The Oregon Clinic | Portland | Oregon | 97220-9428 | — |
| Frontier Clinical Research | Smithfield | Pennsylvania | 15478 | — |
| Gastroenterology Associates P.A. | Greenville | South Carolina | 29615 | — |
| Carolina Health Specialists | Myrtle Beach | South Carolina | 29572 | — |
| West Texas Clinical Research | Lubbock | Texas | 79424 | — |
| Victoria Gastroenterology | Richmond | Texas | 77407 | — |
| Gastroenterology Clinic Of San Antonio P A | San Antonio | Texas | 78229 | — |
| Wellness Clinical Research | San Antonio | Texas | 78232 | — |
| Texas Digestive Disease Consultants | Southlake | Texas | 76092 | — |
| Digestive Health Specialists of Tyler | Tyler | Texas | 75701 | — |
| Care Access Research- Salt Lake City | Salt Lake City | Utah | 84124 | — |
| Burke Internal Medicine and Research | Burke | Virginia | 22015 | — |
| Gastroenterology Associates of Tidewater | Chesapeake | Virginia | 23320 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 268 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05197049, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 25, 2026 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05197049 live on ClinicalTrials.gov.